Results 71 to 80 of about 2,658,494 (306)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Gender and age differences in the presentation of at-risk or probable Developmental Coordination Disorder in adults.

Research in Developmental Disabilities, 2021
BACKGROUND Developmental Coordination Disorder (DCD), also called Dyspraxia, is a common Neurodevelopmental Disorder (NDD) that affects motor coordination with a marked impact on both academic and day-to-day living activities.
M. Cleaton, M. Tal-Saban, E. Hill, A. Kirby   +3 more
semanticscholar   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Postural Control in Children With Developmental Coordination Disorder

Neural Plasticity, 2005
The development of static balance is a basic characteristic of normal motor development. Most developmental motor tests include a measure of static balance. Children with Developmental Coordination Disorder (DCD) often fail this item.
Reint H. Geuze
doaj   +1 more source

Association of Gestational Age at Birth With Subsequent Suspected Developmental Coordination Disorder in Early Childhood in China

JAMA Network Open, 2021
This cohort study investigates the association of gestational age at birth with suspected developmental coordination disorder in early childhood among children aged 3 to 5 years in China.
J. Hua, A. Barnett, Gareth J. Williams, Xiaotian Dai, Yuanjie Sun, Hai-feng Li, Guixia Chen, Lei Wang, Jun-Yan Feng, Yingchun Liu, Lan Zhang, Ling Zhu, Ting-ting Weng, Hongyan Guan, Yue Gu, Ying-Chun Zhou, Andrew Butcher, Wen-Chong Du   +17 more
semanticscholar   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Socio-demographic factors influences on guardians’ perception of Developmental Coordination Disorder among Brazilian schoolchildren

Motriz: Revista de Educacao Fisica, 2018
AIM The objective of this study was to identify socio-demographic factors that are associated with the guardians’ perception of developmental coordination disorder among schoolchildren from seven to ten years old.
Jorge Lopes Cavalcante Neto, Tatiana de Oliveira Sato, Eloisa Tudella   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Studies on Children With Developmental Coordination Disorder in the Past 20 Years: A Bibliometric Analysis via CiteSpace

Frontiers in Psychiatry, 2021
Children with developmental coordination disorder (DCD) have been commonly observed and drawn an increasing amount of attention over the past decades.
Mei-Qin Wu, De-Qing Wu, Chunping Hu, Lai-Sang Iao   +3 more
semanticscholar   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source