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The evolution of developmental mechanisms
Over the past two to three decades, developmental biology has demonstrated that all multicellular organisms in the animal kingdom share many of the same molecular building blocks and many of the same regulatory genetic pathways. Yet we still do not understand how the various organisms use these molecules and pathways to assume all the forms we know ...
Ralf J Sommer
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Probabilistic developmental program evolution
Proceedings of the 2010 ACM Symposium on Applied Computing, 2010A Probabilistic Model Building Genetic Programming technique for automatic program synthesis is introduced. The approach, called Probabilistic Developmental Program Evolution (PDPE), draws on the Probabilistic Incremental Program Evolution (PIPE) learning algorithm, but employs the Developmental Genetic Programming representations of Gene Expression ...
Elmira Ghoulbeigi +1 more
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WIREs Cognitive Science, 2016
Biologists and psychologists are re‐thinking the long‐standing premise of genes as the primary cause of development, a view widely embraced in 20th‐century biology. This shift in thinking is based in large part on: (1) the growing appreciation of the complex, distributed regulatory dynamics of gene expression; and (2) the growing appreciation of the ...
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Biologists and psychologists are re‐thinking the long‐standing premise of genes as the primary cause of development, a view widely embraced in 20th‐century biology. This shift in thinking is based in large part on: (1) the growing appreciation of the complex, distributed regulatory dynamics of gene expression; and (2) the growing appreciation of the ...
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Evolution of developmental traits
Current Opinion in Plant Biology, 2004The evolution of plant development can be studied in many different ways, each of which provides new insights into how plants have been modified over evolutionary time. DNA sequencing shows that most developmental genes are under purifying selection and that obvious adaptive change in proteins is rare.
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Evolution in developmental phenotype space
Current Opinion in Genetics & Development, 2012Developmental systems can produce a variety of patterns and morphologies when the molecular and cellular activities within them are varied. With the advent of quantitative modeling, the range of phenotypic output of a developmental system can be assessed by exploring model parameter space.
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The evolution of developmental regulatory pathways
Current Opinion in Genetics & Development, 2002Evolutionary analysis of the content of developmental regulatory pathways has been advanced by the publication of pairs of complete genome sequences from representative taxonomic groups. Annotation of the fission yeast, rice, and mouse genomes confirms that most regulatory families are shared among eukaryotes but also shows that certain gene families ...
Gibson, Greg, Honeycutt, Emily
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