Results 91 to 100 of about 1,798,625 (305)

Size Polymorphism and Fluctuating Asymmetry of Artemia (Branchiopoda: Anostraca) Populations from the Crimea [PDF]

open access: yesЖурнал Сибирского федерального университета: Серия Биология, 2017
Fluctuating asymmetry (FA) of animals as a measure of ontogenetic stability is widely used in environmental bioindication. Environmental stress leads to increased levels of FA within populations.
Nickolai V. Shadrin, Elena V. Anufriieva
doaj  

Turtle carapace anomalies: the roles of genetic diversity and environment. [PDF]

open access: yesPLoS ONE, 2011
Phenotypic anomalies are common in wild populations and multiple genetic, biotic and abiotic factors might contribute to their formation. Turtles are excellent models for the study of developmental instability because anomalies are easily detected in the
Guillermo Velo-Antón   +2 more
doaj   +1 more source

Stability and roughness of interfaces in mechanically-regulated tissues

open access: yes, 2018
Cell division and death can be regulated by the mechanical forces within a tissue. We study the consequences for the stability and roughness of a propagating interface, by analysing a model of mechanically-regulated tissue growth in the regime of small ...
Salbreux, Guillaume, Williamson, John J.
core   +2 more sources

Waves and patterning in developmental biology: vertebrate segmentation and feather bud formation as case studies [PDF]

open access: yes, 2009
In this article we will discuss the integration of developmental patterning mechanisms with waves of competency that control the ability of a homogeneous field of cells to react to pattern forming cues and generate spatially heterogeneous patterns.
Baker, Ruth E.   +2 more
core   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Session 5: Development, Neuroscience and Evolutionary Psychology [PDF]

open access: yes, 2002
Proceedings of the Pittsburgh Workshop in History and Philosophy of Biology, Center for Philosophy of Science, University of Pittsburgh, March 23-24 2001 Session 5: Development, Neuroscience and Evolutionary ...
Machamer, Peter   +3 more
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

DEVELOPMENTAL INSTABILITY IS GENETICALLY CORRELATED WITH PHENOTYPIC PLASTICITY, CONSTRAINING HERITABILITY, AND FITNESS

open access: yesEvolution; international journal of organic evolution, 2013
Although adaptive plasticity would seem always to be favored by selection, it occurs less often than expected. This lack of ubiquity suggests that there must be trade‐offs, costs, or limitations associated with plasticity. Yet, few costs have been found.
S. Tonsor   +2 more
semanticscholar   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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