Results 101 to 110 of about 1,798,625 (305)
Journal of Orthopaedic Surgery, 2023 Introduction Flatfoot and patellar instability are both developmental limb deformities that occur frequently in adolescents. A high number of patients with both diseases can be seen in clinic, and there are no studies showing a correlation between the ...
Haiyang He +4 more
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Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Developmental Instability and Markers of Schizotypy in University Students
Evolutionary Psychology, 2008 Fluctuating asymmetries (FA) and minor physical anomalies (MPAs) are markers of developmental instability (DI), an index of the degree to which an organism was subject to genomic or environmental stress during development.
Robert J. Thoma +5 more
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Reaction-diffusion models for biological pattern formation [PDF]
, 2001 We consider the use of reaction-diffusion equations to model biological pattern formation and describe the derivation of the reaction-terms for several illustrative examples.
Crampin, E. J., Maini, P. K.
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Robust and Irreversible Development in Cell Society as a General Consequence of Intra-Inter Dynamics
, 1999 A dynamical systems scenario for developmental cell biology is proposed, based on numerical studies of a system with interacting units with internal dynamics and reproduction.
Eigen +22 more
core +2 more sources
Bullying Roles in Changing Contexts: The Stability of Victim and Bully Roles from Primary to Secondary School [PDF]
, 2004 The present study was conducted to predict bullying roles over a six years time period and across contexts differing in the degree of peer hierarchies.
Brodbeck, Felix C. +4 more
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Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Accessory femoral pores in Podarcis muralis from Southern Serbia
Biologica Nyssana, 2011 Abnormalities in scalation are common in lizards. Bilateral asymmetries are frequent, as are supernumerary scales. Factors possibly responsible for such developmental anomalies are inbreeding and environmental stress.
Lazić, M.L., Crnobrnja-Isailović, J.
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