Results 71 to 80 of about 1,798,625 (305)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Fluctuating dental asymmetry in rabbits with familial nonsyndromic coronal suture synostosis

open access: yesDentistry 3000, 2017
Fluctuating dental asymmetry has been linked to conditions of unstable pre- and peri-natal development. Familial, nonsyndromic craniosynostosis disrupts early craniofacial development through localized excessive calvarial ossification leading to the ...
Mae A. Hyre   +5 more
doaj   +1 more source

Understanding obsessive-compulsive personality disorder in adolescence: a dimensional personality perspective [PDF]

open access: yes, 2010
The validity of the Axis II Obsessive-Compulsive Personality Disorder (OCPD) category and its position within the Cluster C personality disorder (PDs) section of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV, APA, 2000) continues to ...
Aelterman, Nathalie   +2 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Asymmetry of frontal bristles and postocular setae in species and hybrids of the Anastrepha fraterculus complex (Diptera, Tephritidae)

open access: yesGenetics and Molecular Biology, 2007
Asymmetry of the frontal bristles and postocular setae was studied in samples from natural populations and laboratory colonies of Anastrepha sp. 1 aff. fraterculus, of A. sp. 2 aff.
João Maria G.A. Souza   +3 more
doaj   +1 more source

Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis

open access: yes, 2000
Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''.
Furusawa, Chikara, Kaneko, Kunihiko
core   +3 more sources

Facial symmetry is positively associated with self-reported extraversion [PDF]

open access: yes, 2007
Fink et al. (2005) reported significant associations between facial symmetry and scores on some of the “big five” personality dimensions derived from self-report data.
Brown, WM, Penton-Voak, IS, Pound, N
core   +1 more source

Developmental instability as an estimator of genetic stress [PDF]

open access: yesHeredity, 2005
To set conservation priorities, scientists should be able to assess the relative threats posed by the effects of loss of genetic variability, inbreeding and outbreeding as these can generate 'genetic stress'. Developmental instability (DI) has been suggested as an indicator of stress, possibly being more sensitive than other measures. However, there is
Pertoldi, C.   +3 more
openaire   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Home - About - Disclaimer - Privacy