Results 281 to 290 of about 1,316,154 (307)

Subventricular Zone‐on‐a‐Chip: A Model to Study Neurogenesis Disruption in Neonatal Intraventricular Hemorrhage

Advanced Science, EarlyView.
A human subventricular zone‐on‐a‐chip is developed to model intraventricular hemorrhage (IVH) in preterm infants. This platform enables the study of inflammation‐driven neurogenic disruption. Exposure to hemorrhagic cerebrospinal fluid and red blood cell lysate activated inflammatory pathways, with IL1B emerging as a key mediator.
Laura Nicoleti Zamproni, Begüm Gökçe, Magnus Gram, Coco Holliday, Aylin Sendemir, Marimélia Aparecida Porcionatto, Anna Herland   +6 more
wiley   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Editorial: Decoding complexity: genomic, epigenomic, and environmental dynamics in developmental and neurogenetic disorders. [PDF]

Front Genet
Fiorenzano A, Azevedo L.
europepmc   +1 more source

Laser Ultrasound Super‐Resolution Imaging for Multi‐Parametric Non‐Invasive Volumetric Characterization of Brain Cancer

Advanced Science, EarlyView.
Laser ultrasound super‐resolution imaging (LUSSI) leverages laser‐generated ultrasound for functional 3D transcranial imaging of brain tumor vasculature. Combined with optoacoustic tomography, it is demonstrated in a glioblastoma model, revealing structural abnormalities, compressed vessels, hemorrhages, and hypoxic regions.
Daniil Nozdriukhin, Yi Chen, Shuxin Lyu, Daniel Razansky, Xosé Luís Deán‐Ben   +4 more
wiley   +1 more source

Correction: DNA methylation profiles of long-term cannabis users in midlife: a comprehensive evaluation of published cannabis-associated methylation markers in a representative cohort. [PDF]

Mol Psychiatry
Meier MH, Sugden K, Moffitt TE, Williams BS, Bourassa KJ, Houts R, Ramrakha S, Theodore R, Caspi A.   +8 more
europepmc   +1 more source

Editorial: Cellular and synaptic mechanisms in the auditory system in health and disease. [PDF]

Front Cell Neurosci
Englitz B, Keine C.
europepmc   +1 more source

The Neuroscience of Social Exclusion: Developmental and Public Health Implications Across the Life-Course

Anayra Túa-López, Fabián Román
openalex   +1 more source

Author Correction: Brain tumors induce widespread disruption of calvarial bone and alteration of skull marrow immune landscape. [PDF]

Nat Neurosci
Dubey A, Yamashita E, Stangeland B, Abbas I, Fooksman D, Harris RA, Palmer GM, Koba WR, Zhang J, Himes BT, Lu OR, Ho WS, Kuiper RV, Huffman D, Wu Z, Uchida Y, Ishii M, Welch RL, Fiedler AF, Reynolds D, Hosainey SAM, Dobrenis K, Ye Q, Fisher K, Killian N, Stanley ER, Eskandar E, Behnan J.   +27 more
europepmc   +1 more source

Computationally Probing the Role of Time-Limited Neuronal Plasticity in Early Visual Development. [PDF]

Dev Sci
Vogelsang M, Vogelsang L, Sinha P.
europepmc   +1 more source

Predictive coding and attention in developmental cognitive neuroscience and perspectives for neurodevelopmental disorders

Anne-Lise Marais, Nadège Roche‐Labarbe   +1 more
openalex   +1 more source