Results 51 to 60 of about 239,863 (300)

Enhancing Engagement and Treatment Efficacy in Youth and Families with Persistent Trauma Exposure

Children
Emerging research highlights important distinctions in symptomatology between Posttraumatic Stress Disorder (PTSD) resulting from a single, discrete event, complex interpersonal traumas in the past, and the pervasive effects of chronic, ongoing complex ...
Jana Pressley, Joseph Spinazzola, Irene Jun, Sophia N. Hamilton, Julian D. Ford, Richard Kagan   +5 more
doaj   +1 more source

Developmental predictors of young adult borderline personality disorder: a prospective, longitudinal study of females with and without childhood ADHD

BMC Psychiatry, 2023
Background Research on the precursors of borderline personality disorder (BPD) reveals numerous child and adolescent risk factors, with impulsivity and trauma among the most salient. Yet few prospective longitudinal studies have examined pathways to BPD,
Sinclaire M O'Grady, S. Hinshaw
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The affects of forgiveness on the symptoms of posttraumatic stress disorder as a result of sexual trauma [PDF]

, 2007
This study continues research pertaining to the affects of forgiveness on Posttraumatic Stress Disorder (PTSD) symptoms resulting from sexual trauma. The research question asked whether or not the ability to forgive would reduce, increase, or have no ...
Johnston, Sandra K., Sandra K. Johnston
core  

Complex PTSD: research directions for nosology/assessment, treatment, and public health [PDF]

European Journal of Psychotraumatology, 2015
Complex posttraumatic stress disorder (CPTSD) in children and adolescents extends beyond the core PTSD symptoms to dysregulation in three psychobiological domains: (1) emotion processing, (2) self-organization (including bodily integrity), and (3 ...
Julian D. Ford
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Traumatic incident reduction: A suitable technique for South African social work practice settings

Health SA Gesondheid: Journal of Interdisciplinary Health Sciences, 2019
It is part of South African social workers’ responsibilities to attend promptly and appropriately to victims of trauma. Overstrained and limited resources in communities influence the availability of debriefing services to traumatised community members ...
H. Marili Williams, Elizabeth C. Erlank
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Keloids: An unwanted spontaneity in Rubinstein-Taybi Syndrome

Indian Journal of Dermatology, 2015
Rubinstein-Taybi syndrome (RTS) is a rare developmental disorder comprising of mental retardation, unusual facial appearance, broad thumbs, and big toes.
P Shilpashree, Ashok Kumar Jaiswal, Priyadarshini M Kharge   +2 more
doaj   +1 more source