Results 271 to 280 of about 242,754 (286)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Factors associated with meeting the recommendations for physical activity, sedentary behavior, and sleep in adolescents: a cross-sectional study. [PDF]

Rev Paul Pediatr
Rocha KBDS, Feitosa SB, Wanderley Junior RS, Costa ADS, Barbosa Filho VC, Barros MVG, Hardman CM, Queiroz DDR.   +7 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Deviance detection and regularity sensitivity in dissociated neuronal cultures. [PDF]

Front Neural Circuits
Zhang Z, Yaron A, Akita D, Shiramatsu TI, Chao ZC, Takahashi H.   +5 more
europepmc   +1 more source

A Dynamic Foraging Habitat Distribution Estimate for Green Turtles in the Great Barrier Reef. [PDF]

Ecol Evol
Webster E, Duce S, Limpus C, Murray N, Patterson T, Pillans R, Shimada T, Hamann M.   +7 more
europepmc   +1 more source

Temperature-driven shifts in foraging behaviour during larval development in a dragonfly. [PDF]

Sci Rep
Hogreve J, Johansson F, Suhling F.
europepmc   +1 more source

Values of the Deviance Information Criterion (DIC) for the different serological model scenarios.

Celia Hamouche (21587708), Jennifer Pradel (11218098), Nonito Pagès (3476309), Véronique Chevalier (3122862), Sylvie Lecollinet (125539), Jonathan Bastard (9972094), Benoit Durand (2577400)   +6 more
openalex   +1 more source

The influence of different genders on the relationship between the size and density of paravertebral muscles and subcutaneous adipose tissue and the proximal femoral bone in elderly people with hip fractures. [PDF]

BMC Musculoskelet Disord
Cai P, Li Y.
europepmc   +1 more source