Results 71 to 80 of about 242,754 (286)
Minimum Average Deviance Estimation for Sufficient Dimension Reduction
, 2016 Sufficient dimension reduction reduces the dimensionality of data while preserving relevant regression information. In this article, we develop Minimum Average Deviance Estimation (MADE) methodology for sufficient dimension reduction.
Adragni, Kofi P. +2 more
core +1 more source
The Social World of Content Abusers in Community Question Answering [PDF]
, 2015 Community-based question answering platforms can be rich sources of information on a variety of specialized topics, from finance to cooking. The usefulness of such platforms depends heavily on user contributions (questions and answers), but also on ...
Bonchi, Francesco +4 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Sociétés et Jeunesses en Difficulté, 2008 This article uses a few specific examples to demonstrate how the social capital which facilitates the successful integration of young people into a low income housing environment becomes a handicap as soon as one gets out of it, whether in terms of ...
Muriel Epstein
doaj
Bayesian Modelling of Inseparable Space-Time Variation in Disease Risk [PDF]
, 1998 This paper proposes a unified framework for a Bayesian analysis of incidence or mortality data in space and time. We introduce four different types of prior distributions for space $\times$ time interaction in extension of a model with only main effects.
Knorr-Held, Leonhard
core +4 more sources
Positive Deviance Cases: Their Value for Development Research, Policy, and Practice [PDF]
, 2022 Melani Cammett
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Constructive Deviance, Destructive Deviance and Personality: How do they interrelate? [PDF]
In recent years deviant behavior in organizations has drawn increasing attention. However, surprisingly little research has focused on constructive rather than destructive deviance.
Aharon Tziner, Moran Bodankin
core
The Deviance of the Zookeepers [PDF]
, 2013 In May 1968 Alvin Gouldner published his attack on the ‘Becker School’ of sociology (‘The Sociologist as Partisan’). The essay was a sometimes sarcastic and brutal but characteristically insightful and sharp critique of what he called the ‘Becker School’
O-brien, Martin Anthony
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source