Results 101 to 110 of about 1,402,537 (260)

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

open access: yesAdvanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma   +13 more
wiley   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

open access: yesAdvanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang   +11 more
wiley   +1 more source

An Engineered Biomimetic Nanoreactor With Cascade Functions for Targeted and Combinatorial Therapy of Ischemic Stroke

open access: yesAdvanced Healthcare Materials, EarlyView.
Preparation of RVG‐modified erythrocyte membrane‐coated HMPB nanocarriers loaded with L‐arginine and NBP (RM@HPAN) and its neuroprotective mechanism. After intravenous injection, RM@HPAN achieves prolonged circulation, RVG‐29‐mediated BBB penetration, and ischemic accumulation.
Shaofa Li   +9 more
wiley   +1 more source

Lignin Mimicking Protein Methylation Augments the Efficacy of FOLFOX Chemotherapy by Anchoring Thymidylate Synthase

open access: yesAdvanced Materials, EarlyView.
Lignin‐mimicking protein methylation can enhance the efficacy and mitigate the toxicity of the classic FOLFOX chemotherapy regimen. ABSTRACT FOLFOX has served as the standard chemotherapy regimen for advanced stages, specifically in the treatment of pancreatic, colorectal, and bladder cancers.
Shiyao Song   +14 more
wiley   +1 more source

The Role of Parental Monitoring and Affiliation with Deviant Peers in Adolescents’ Sexual Risk Taking: Toward an Interactional Model

open access: yesInternational Journal of High Risk Behaviors and Addiction, 2013
Adolescence is considered as an important phase for beginning sexual high risk behaviors that increases the possibility of negative, unpleasant and problematic consequences like unwanted pregnancy and probability of copulative disease transmission.To determine the prevalence of sexual risk taking among students in Tehran and to develop and test a model
Ahmadi, Khodabakhsh   +4 more
openaire   +2 more sources

Wearable Morphology‐Adaptive in‐Ear Device With Active Cleansing Capability for Multimodal Health Monitoring

open access: yesAdvanced Materials, EarlyView.
We present SCIENCE, an in‐ear multimodal physiological monitor featuring two key innovations. Water‐triggered morphological expansion (a 2‐mm cylinder to a 9‐mm spindle) achieves conformal adaptation across complex canal geometries. Simultaneously, active biofouling mitigation disrupts cerumen barriers, reducing sensor‐skin impedance by 20%.
Shuyun Zhuo   +3 more
wiley   +1 more source

The prevalence and risk factors of conduct disorder among juvenile delinquents in China

open access: yesHumanities & Social Sciences Communications
Conduct disorders (CDs) are common in juvenile justice cases, but their prevalence varies across regions. It is useful to help people comprehend the incidence and risk factors for CDs in the judicial environment.
Qinhong Xie   +5 more
doaj   +1 more source

Deterministic Field‐Free Switching of Perpendicular Magnetization by Bulk Mirror Symmetry Broken Bi1−xSbx (012) with High Spin Hall Conductivity

open access: yesAdvanced Materials, EarlyView.
Crystal orientation and domain engineering enable bulk mirror symmetry breaking in Bi1−xSbx, resulting in ultralow current‐induced switching of perpendicular magnetization without an external field. By exploiting single‐domain Bi1−xSbx (012), the authors demonstrate an out‐of‐plane spin Hall conductivity of ∼1.12×105ℏ2eΩ−1m−1$ \sim \!1.12 \ensuremath ...
Seungwon Rho   +6 more
wiley   +1 more source

Evaluations of and reasoning about normative and deviant ingroup and outgroup members: Development of the black sheep effect. [PDF]

open access: yes, 2014
Research with adults has demonstrated a “black sheep effect” (BSE) whereby, relative to evaluations of normative group members, ingroup deviants are derogated more than outgroup deviants.
Rutland, Adam   +9 more
core   +1 more source

Descriptors to Dynamics: A Materials and Device Perspective on in‐Materio Physical Reservoir Computing for Neuromorphic Edge Intelligence

open access: yesAdvanced Materials, EarlyView.
Intrinsic material dynamics are harnessed as computational resources for neuromorphic in‐materio physical reservoir computing. Defects, ionic motion, interfaces, percolation, geometry, and biasing shape transient states that provide fading memory, nonlinearity, and high‐dimensional projection for simple readout. A descriptor‐to‐dynamics framework links
Kshitij RB Singh   +5 more
wiley   +1 more source

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