Results 61 to 70 of about 107,124 (326)

Reduced Muscular Carnosine in Proximal Myotonic Myopathy—A Pilot 1H‐MRS Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Myotonic dystrophy type 2 (proximal myotonic myopathy, PROMM) is a progressive multisystem disorder with muscular symptoms (proximal weakness, pain, myotonia) and systemic manifestations such as diabetes mellitus, cataracts, and cardiac arrhythmias.
Alexander Gussew   +11 more
wiley   +1 more source

Lessons learnt from the transport provision on the island of Ireland – political observations [PDF]

open access: yesTransport Problems, 2013
The paper delineates the core issues surrounding political, socio-economic, and territorial implications on a number of transport issues on the island of Ireland by looking at the record of transport in the early 20th century, concentrating on the ...
Banihan GUNAY, Gerard McGRADY
doaj  

THE ROOTS OF BREXIT: CONFLICT OF IDENTITIES IN THE UNITED KINGDOM

open access: yesКонтуры глобальных трансформаций: политика, экономика, право, 2017
The United Kingdom has been developing due to political compromise that has a positive impact over British political system to solve dichotomy between the principles of Parliament sovereignty and regional home rule.
N. V. Eremina
doaj   +1 more source

Reflections on the Impact of Devolution in California [PDF]

open access: yes, 2000
Provides a definition of devolution, an overview of the context of recent policy changes, a review of recent policy changes, an overview of significant upcoming policy debates, and a discussion of the implications of devolution for ...
Jean Ross
core  

Acoustic Measures Capture Speech Dysfunction in Spinocerebellar Ataxia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxias (SCA) are hereditary cerebellar degenerative disorders with a common feature of dysarthria, involving impaired phonatory and articulatory control of speech, thereby affecting social communication. In this study, we investigated whether acoustic measures could objectively measure speech dysfunction and identify
Zena Fadel   +5 more
wiley   +1 more source

The devolution paradigm: theoretical critiques and the case of Kenya [PDF]

open access: yes, 2019
Devolution’s assumptions presume democracy, yet its proponents view it as an antidote to repressive centralized states, where its assumptions do not hold.
Mueller, Susanne D.
core  

Preferences, Perceptions, and Veto Players: Explaining Devolution Negotiation Outcomes in the Canadian Territorial North [PDF]

open access: yes, 2012
Since the early part of the 20th century, the federal government has engaged in a long and slow process of devolution in the Canadian Arctic. Although the range of powers devolved to the territorial governments has been substantial over the years, the ...
Abele   +22 more
core   +2 more sources

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

The 2024 General Election in Scotland: Persistent Instability or Realignment?

open access: yesRevue Française de Civilisation Britannique
On 4 July 2024, the number of Scottish Labour MPs soared from 1 in 2019 to 37, mostly at the expense of the SNP which retained only 9 MPs. This resulted both from the momentum for Labour at UK level and from the SNP’s growing divisions over policies and ...
Edwige Camp-Pietrain
doaj   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung   +7 more
wiley   +1 more source

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