Results 61 to 70 of about 18,042 (296)

The 2017 General Election in Scotland: a Return to Multi-party Politics?

Revue Française de Civilisation Britannique, 2018
Although Scotland had long been a Labour stronghold, devolution soon appeared to have served as a political platform for the nationalists who were able to assert their domination of Scottish politics after they obtained both an overall majority of seats ...
Fiona Simpkins
doaj   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

The global trend towards devolution and its implications. [PDF]

, 2003
Globalisation has been accompanied by an equally global tendency towards devolution of authority and resources from nation-states to regions and localities that takes on various forms, depending upon which actors are driving the decentralisation efforts.
Rodiguez-Pose, A, Gill, Nick, Gill, Nicholas, Rodríguez-Pose, Andrés   +3 more
core   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Lessons learnt from the transport provision on the island of Ireland – political observations [PDF]

Transport Problems, 2013
The paper delineates the core issues surrounding political, socio-economic, and territorial implications on a number of transport issues on the island of Ireland by looking at the record of transport in the early 20th century, concentrating on the ...
Banihan GUNAY, Gerard McGRADY
doaj  

THE ROOTS OF BREXIT: CONFLICT OF IDENTITIES IN THE UNITED KINGDOM

Контуры глобальных трансформаций: политика, экономика, право, 2017
The United Kingdom has been developing due to political compromise that has a positive impact over British political system to solve dichotomy between the principles of Parliament sovereignty and regional home rule.
N. V. Eremina
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Book Review - Devolution and Localism in England

, 2016
In the autumn of 2015 the first Chancellor of a Conservative Government to address a Conservative Party Conference in 18 years, George Osborne, famously, or notoriously, proclaimed that England was in the midst of a devolution revolution.
Muldoon-Smith, Kevin, Greenhalgh, Paul, Paul Greenhalgh, Kevin Muldoon-Smith   +3 more
core   +1 more source

The 2024 General Election in Scotland: Persistent Instability or Realignment?

Revue Française de Civilisation Britannique
On 4 July 2024, the number of Scottish Labour MPs soared from 1 in 2019 to 37, mostly at the expense of the SNP which retained only 9 MPs. This resulted both from the momentum for Labour at UK level and from the SNP’s growing divisions over policies and ...
Edwige Camp-Pietrain
doaj   +1 more source