Results 311 to 320 of about 496,062 (355)

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu   +7 more
wiley   +1 more source

Mitochondrial Oxygen Consumption and Immunocytochemistry of Human Dental Pulp Stem Cell Following 808 nm PBM Therapy: A 3D Cell Culture Study

open access: yesJournal of Biophotonics, EarlyView.
808 nm photobiomodulation could enhance mitochondrial respiration and upregulate osteogenic protein expression in hDPSCs within a 3D hydrogel model, suggesting its potential in regenerative therapies. Further research is needed to optimize treatment protocols for clinical applications.
Simone L. Sleep   +5 more
wiley   +1 more source

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