Results 81 to 90 of about 269,360 (302)

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

The Effects of Dexamethasone on Postoperative Complications After Surgical Removal of Impacted Lower Third Molar Teeth

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2014
The purpose of this study was to evaluate the effects of dexamethasone on postoperative complications after surgical removal of impacted lower third molar.
Haider Ali Rassul, Ahmad Fliah Hassan, Athil Adnan Raheem, Hajer Ibrahem   +3 more
doaj   +1 more source

Inhibitory Effects of Dexamethasone on Hepatocyte Growth Factor–Induced DNA Synthesis and Proliferation in Primary Cultures of Adult Rat Hepatocytes

Journal of Pharmacological Sciences, 2011
We investigated the effects of dexamethasone on hepatocyte growth factor (HGF)-induced DNA synthesis and proliferation in serum-free primary cultures of adult rat hepatocytes.
Mitsutoshi Kimura, Hajime Moteki, Masahiko Ogihara   +2 more
doaj   +1 more source

Dexamethasone for the prevention of postoperative atrial fibrillation

, 2015
BACKGROUND: Postoperative atrial fibrillation (AF) is a common complication after cardiac surgery. Inflammation is believed to play a pivotal role in the etiology of postoperative AF.
van Osch, Dirk, van Dijk, Diederik, DExamethasone for Cardiac Surgery (DECS) Study Group, Kluin, Jolanda, Doevendans, Pieter A., Nathoe, HM, Doevendans, Pieter A, Jacob, Kirolos, Jacob, Kirolos A., Dieleman, Jan M., Nathoe, Hendrik M., Dieleman, Jan M   +11 more
core   +1 more source

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

Advanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim, In Ah Kwon, Bo Seop Jeong, Hyo Seon Kim, Joo‐Hwan Park, Sung Jean Park, Sang‐Rae Lee, Youngki Lee, Dongwoo Khang   +8 more
wiley   +1 more source

Plasma dexamethasone levels in children given the dexamethasone suppression test [PDF]

, 1990
To determine whether children who demonstrate dexamethasone suppression test (DST) nonsuppression have lower plasma dexamethasone levels than DST suppressors, we administered the DST to 73 patients ranging in age from 5-14 years.
Alessi, Norman E., Naylor, Michael W., Greden, John F.   +2 more
core   +1 more source

Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond

Advanced Science, EarlyView.
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu, Gewei Yan, Zhentao She, Yingzhu He, Kangqi Liu, Jianan Qu   +5 more
wiley   +1 more source

Evaluation of efficacy dexamethasone intravitreal implant compared to treatment with anti-VEGF in the treatment of diabetic macular edema

, 2014
1. Objective: The study compares the effectiveness of an intravitreal slow-release dexamethasone implant respect to an intravitreal injection of a anti-VEGF, ranibizumab, in the treatment of diabetic macular edema (DME). 2.
MAZZEO, FRANCESCO, Giuseppe La Torre, PACELLA, Elena, S. Casale, Fernanda Pacella, C. Merisola, Elena Pacella, Concetta Merisola, LA TORRE, Giuseppe, Paolo Turchetti, Tommaso Lenzi, PACELLA, FERNANDA, TURCHETTI, PAOLO, LENZI, TOMMASO, Pietro Luchetti, Silvia Casale, Francesco Mazzeo, P. Luchetti   +17 more
core   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Transcriptional Co‐Activator With PDZ Binding Motif (TAZ) Inhibits Dexamethasone‐Induced Muscle Atrophy via mTOR Signalling

Journal of Cachexia, Sarcopenia and Muscle
Background Glucocorticoid therapy has a beneficial effect in several diseases, but chronic treatment has adverse effects, including muscle atrophy, which refers to the gradual decrease in muscle mass, size and strength.
Kyung Min Kim, Ho Taek Oh, Youjin Do, Gi Don Yoo, Woong Heo, Jeekeon Park, Hyejin Yang, Suh Jin Yoon, Mi Ran Byun, Eun Sook Hwang, Jeong‐Ho Hong   +10 more
doaj   +1 more source