Results 81 to 90 of about 250,188 (305)

Plasma dexamethasone levels in children given the dexamethasone suppression test [PDF]

, 1990
To determine whether children who demonstrate dexamethasone suppression test (DST) nonsuppression have lower plasma dexamethasone levels than DST suppressors, we administered the DST to 73 patients ranging in age from 5-14 years.
Alessi, Norman E., Naylor, Michael W., Greden, John F.   +2 more
core   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source

Dexamethasone for the prevention of postoperative atrial fibrillation

, 2015
BACKGROUND: Postoperative atrial fibrillation (AF) is a common complication after cardiac surgery. Inflammation is believed to play a pivotal role in the etiology of postoperative AF.
van Osch, Dirk, van Dijk, Diederik, DExamethasone for Cardiac Surgery (DECS) Study Group, Kluin, Jolanda, Doevendans, Pieter A., Nathoe, HM, Doevendans, Pieter A, Jacob, Kirolos, Jacob, Kirolos A., Dieleman, Jan M., Nathoe, Hendrik M., Dieleman, Jan M   +11 more
core   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Comparing the Effect of Paracetamol, Dexamethasone, and Paracetamol plus Dexamethasone on Prevention of Postoperative Headache in Pregnant Women Undergoing Cesarean Section with Spinal Anesthesia

مجله دانشکده پزشکی اصفهان, 2018
Background: This study aimed to compare the effect of paracetamol, dexamethasone, and paracetamol plus dexamethasone on prevention of postoperative headache in pregnant women undergoing cesarean section with spinal anesthesia.
Mitra Jabalameli, Mahsa Payandeh
doaj   +1 more source

Adjunctive use of intravitreal dexamethasone in presumed bacterial endophthalmitis

, 2009
Includes abstract. Includes bibliographical references (leaves 33-36)
Albrecht, Eric
core  

Evaluation of efficacy dexamethasone intravitreal implant compared to treatment with anti-VEGF in the treatment of diabetic macular edema

, 2014
1. Objective: The study compares the effectiveness of an intravitreal slow-release dexamethasone implant respect to an intravitreal injection of a anti-VEGF, ranibizumab, in the treatment of diabetic macular edema (DME). 2.
MAZZEO, FRANCESCO, Giuseppe La Torre, PACELLA, Elena, S. Casale, Fernanda Pacella, C. Merisola, Elena Pacella, Concetta Merisola, LA TORRE, Giuseppe, Paolo Turchetti, Tommaso Lenzi, PACELLA, FERNANDA, TURCHETTI, PAOLO, LENZI, TOMMASO, Pietro Luchetti, Silvia Casale, Francesco Mazzeo, P. Luchetti   +17 more
core   +1 more source

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

INDEX study: intravenous dexamethasone palmitate for prophylaxis of postoperative nausea and vomiting: a study protocol for a randomised controlled study

BMJ Open
Introduction Dexamethasone is commonly used to prevent postoperative nausea and vomiting (PONV). However, PONV is an unresolved complex problem; even with preoperative dexamethasone administration, 14.0%–26.3% of patients undergoing minimally invasive ...
Hao Ren, Fang Luo, Chunmei Zhao, Ying Shen, Lan Meng, Linsong Yuan   +5 more
doaj   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source