Results 231 to 240 of about 163,143 (320)

Breaking barriers: Smart vaccine platforms for cancer immunomodulation

Cancer Communications, EarlyView.
Abstract Despite significant advancements in cancer treatment, current therapies often fail to completely eradicate malignant cells. This shortfall underscores the urgent need to explore alternative approaches such as cancer vaccines. Leveraging the immune system's natural ability to target and kill cancer cells holds great therapeutic potential ...
Mohammad Mahmoudi Gomari, Taha Ghantabpour, Nima Pourgholam, Neda Rostami, Stephen M. Hatfield, Farzaneh Namazifar, Shadi Abkhiz, Seyed Sadegh Eslami, Mahsa Ramezanpour, Mahsa Darestanifarahani, Igor Astsaturov, Sidi A. Bencherif    +11 more
wiley   +1 more source

Oral lactoferrin as a treatment of pediatrics' anemia resulted from chronic kidney diseases: a randomized controlled trial. [PDF]

Sci Rep
Hegazy SK, Koura MSE, Elharoun MS.
europepmc   +1 more source

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

Chemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang, Huiling Liu, Bingdong Zhu, Wen Li, Xue Han, Jiaojiao Fu, Renjie Luo, Haiyan Wang, Jinxia Wang   +8 more
wiley   +1 more source

Reticuloendothelial system blockade does not enhance siRNA-LNP circulation or tumor accumulation in mice. [PDF]

Int J Pharm X
Escudé Martinez de Castilla P, Estapé Senti M, Erkens S, van Weerden WM, Kooijmans SAA, Fens MH, Vader P, Schiffelers RM.   +7 more
europepmc   +1 more source

Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential

ChemBioEng Reviews, EarlyView.
This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona, Kaveh Shahbaz, Saeid Baroutian   +2 more
wiley   +1 more source

Network pharmacology and <i>in vivo</i> study: Unraveling the therapeutic mechanisms of <i>Panax ginseng</i> in potentially treating ulcerative colitis. [PDF]

World J Gastroenterol
Qin Y, Zhang RY, Zhang Y, Zhao YQ, Hao HF, Wang JP.   +5 more
europepmc   +1 more source

A Versatile Fabrication Route for Screening of Block Copolymer Membranes in Bioprocessing. [PDF]

ACS Omega
Meng K, Alvarez-Fernandez A, Guldin S, Bracewell DG.   +3 more
europepmc   +1 more source

Artificial Lipidation of Antifungal Proteins and Antifungal Behavior: A Case Study with Cholesterylation

ChemBioChem, EarlyView.
The antifungal behavior of artificial palmitoylated or cholesterylated chitinase domain is studied from biological, chemical, and physical properties, highlighting the importance of the chemical properties of the lipid moiety covalently attached to chitinase domain to obtain effective antifungal activity by artificial protein lipidation through a ...
Muhammad Safaat, Kazuki Uchida, Pugoh Santoso, Ryo Sato, Toki Taira, Rie Wakabayashi, Masahiro Goto, Noriho Kamiya   +7 more
wiley   +1 more source

Inhibition of chondroitin sulphate-degrading enzyme Chondroitinase ABC by dextran sulphate. [PDF]

Glycoconj J
Dalal S, Pathak R, Moh EXS, Packer NH.
europepmc   +1 more source

Engineering and Structural Elucidation of a Sac7d‐Derived IgG Fc‐Specific Affitin and Its Application for the Light‐Controlled Affinity Purification of Antibodies

ChemBioChem, EarlyView.
An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl, Andreas Eichinger, Peter Mayrhofer, Markus R. Anneser, Mauricio Testanera, Kilian Rauscher, Matthias Lenz, Arne Skerra   +7 more
wiley   +1 more source