Results 271 to 280 of about 100,399 (378)

Engineering DNA nanopores: from structural evolution to sensing and transport. [PDF]

Mater Today Bio
Liu F, Arai T, Guo D, Jiang Z, Zhao L, Liu X.   +5 more
europepmc   +1 more source

Pharmaceutical production problems detected by adverse drug reactions reports: a documentary study from the German Democratic Republic, 1982 to 1990 [PDF]

, 2012
Aagaard, Lise, Hansen, Ebba Holme, Meyer, Ulrich, Schaefer, Marion   +3 more
core   +1 more source

Progastrin Promotes Colorectal Cancer Stem Cell‐Like Properties via the Receptor PZR

Advanced Science, EarlyView.
The tumor microenvironment supports colorectal cancer (CRC) progression by maintaining cancer stem cells (CSCs) through progastrin (PG). This study identifies Protein Zero‐Related protein (PZR) as an essential receptor for PG activity, promoting CSC‐like signaling via SHP2/SRC/β‐catenin.
Julie Nguyen, Marie Lafitte, Maud Barbery, Kevin Espie, Maya Jeitany, Romain Larive, Jihane Vitre, Conception Paul, Yvan Boublik, Elise Fourgous, Valérie Simon, Audrey Sirvent, Madeline Neiveyans, Steeve Thirard, Lucile Bansard, Morgan Maillard, Nathalie Coutry, Jacques Colinge, Philippe Jay, Pierre Martineau, Michael Hahne, Julie Pannequin, Serge Roche   +22 more
wiley   +1 more source

A comparison of Pluronic F-68, low molecular weight dextran, mannitol, and saline as priming agents in the heart-lung apparatus

, 1968
Alan C. Hymes, M.H. Safavian, Augustine Arbulu, Peter Baute   +3 more
openalex   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

3D bioprinting for the production of a perfusable vascularized model of a cancer niche. [PDF]

Front Bioeng Biotechnol
Maggiotto F, Bova L, Micheli S, Pozzer C, Fusco P, Sgarbossa P, Billi F, Cimetta E.   +7 more
europepmc   +1 more source

The Probiotic Parabacteroides johnsonii Ameliorates Metabolic Disorders Through Promoting BCAAs to BSCFAs Conversion

Advanced Science, EarlyView.
Clinical discovery and the proposed underlying mechanism by how P. johnsonii ameliorated metabolic disorders. Abstract The gut bacterium Parabacteroides spp. is increasingly recognized for its therapeutic potential in treating metabolic disorders. However, the role of Parabacteroides johnsonii in metabolic disorders is never reported.
Yimeng Chen, Shujun Jiang, Haolu Wang, Mengzhen Si, Haixia Wu, Xinyi Liang, Shenmeng Yao, Yanliang Zhang, Xiaodong Wen, Jie Yang   +9 more
wiley   +1 more source

Tunneling Nanotube‐Mediated Transcellular Autophagy Alleviates Cadmium Induced Hepatocyte Injury

Advanced Science, EarlyView.
ROS accumulation is an important upstream signal for activating transcellular autophagy. Incomplete autophagy and TNT formation are necessary conditions for activating transcellular autophagy, and the disruption of the autophagic fusion mechanism is a trigger for activating transcellular autophagy.
Tao Wang, Li Wang, Jian Sun, Yan Chen, Waseem Ali, Yonggang Ma, Ruilong Song, Xishuai Tong, Jiaqiao Zhu, Yan Yuan, Jianhong Gu, Jianchun Bian, Zongping Liu, Hui Zou   +13 more
wiley   +1 more source

<i>In situ</i> monitoring of barrier function on-chip <i>via</i> automated, non-invasive luminescence sensing.

Lab Chip
Schellberg BG, Koppes AN, Koppes RA.
europepmc   +1 more source

Macrophage‐Mediated Transport of Insoluble Indirubin Induces Hepatic Injury During Intestinal Inflammation

Advanced Science, EarlyView.
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu, Jingchun Shi, Heung‐Lam Mok, Cheng Lyu, Junbang Chen, Chunhua Huang, Hongyan Qin, Chengyuan Lin, Hor‐Yue Tan, Zhaoxiang Bian   +9 more
wiley   +1 more source