Results 61 to 70 of about 81 (78)

Structure of mitogen-activated protein kinase kinase 1 in the DFG-out conformation

Acta Crystallographica Section F, Structural Biology Communications, 2021
Masaaki Sawa, Tsuyoshi Shirai, Toshiji Tada   +2 more
exaly  

Structure-based drug design enables conversion of a DFG-in binding CSF-1R kinase inhibitor to a DFG-out binding mode

Bioorganic and Medicinal Chemistry Letters, 2010
Marvin Meyers, Mihir D Parikh, John J Parlow   +2 more
exaly  

Biphenyl amide p38 kinase inhibitors 4: DFG-in and DFG-out binding modes

Bioorganic and Medicinal Chemistry Letters, 2008
Paul Bamborough
exaly  

Structural Characterization of the Aurora Kinase B “DFG-flip” Using Metadynamics

AAPS Journal, 2019
Naga Rajiv Lakkaniga, Shuxing Zhang, Hong-Yu Li   +2 more
exaly  

Insights into MAPK p38α DFG flip mechanism by accelerated molecular dynamics

Bioorganic and Medicinal Chemistry, 2010
Francesca De Rienzo, M Cristina Menziani   +1 more
exaly  

Enhanced selectivity profile of pyrazole-urea based DFG-out p38α inhibitors

Bioorganic and Medicinal Chemistry Letters, 2010
Haile Tecle, Jessie M English
exaly  

Preparation of activated flavor precursor DFG, N-(1-deoxy-1-fructosylglycine) by combination of vacuum evaporation and closed system heating steps

Food Chemistry, 2018
Tomáš Davídek, Karin Kraehenbuehl
exaly  

The dynamic switch mechanism that leads to activation of LRRK2 is embedded in the DFGψ motif in the kinase domain

Proceedings of the National Academy of Sciences of the United States of America, 2019
Friedrich W Herberg, Sven H Schmidt, Matthias Joseph Knape   +2 more
exaly  

DFG-in and DFG-out homology models of TrkB kinase receptor: Induced-fit and ensemble docking

Journal of Molecular Graphics and Modelling, 2010
Pierfausto Seneci, Anna Bernardi, Črtomir Podlipnik   +2 more
exaly  

Discovery of a Type III Inhibitor of LIM Kinase 2 That Binds in a DFG-Out Conformation

ACS Medicinal Chemistry Letters, 2015
Nicole Goodwin, Giovanni Cianchetta, Jason Allen   +2 more
exaly