Results 11 to 20 of about 3,573 (169)

Molecular pathways and therapeutic strategies in dermatofibrosarcoma protuberans (DFSP) [PDF]

EXCLI Journal : Experimental and Clinical Sciences
Dermatofibrosarcoma Protuberans (DFSP) is a rare soft tissue sarcoma distinguished by its infiltrative growth pattern and recurrence potential. Understanding the molecular characteristics of DFSP is essential for enhancing its diagnosis, prognosis, and ...
Harpreet Singh, Heena Bholaram Choudhary, Deepa Satish Mandlik, Manoj Subhash Magre, Sourav Mohanto, Mohammed Gulzar Ahmed, Bhuvnesh Kumar Singh, Arun Kumar Mishra, Arvind Kumar, Amrita Mishra, T. Venkatachalam, Hitesh Chopra   +11 more
doaj   +2 more sources

Overcoming Mohs Limitations in Treating DFSP: Retrospective Analysis of a Novel Excision Technique

Life
Dermatofibrosarcoma protuberans (DFSP) is a rare, soft-tissue sarcoma characterized by dermal, finger-like projections and high local recurrence rates.
Rami Shoufani, Ariel Berl, Ofir Shir-az, Deborah Kidron, Din Mann, Noam Castel, Avshalom Shalom   +6 more
doaj   +2 more sources

Conventional and contrast-enhanced ultrasound in the differential diagnosis of recurrent dermatofibrosarcoma protuberans and postoperative scar

BMC Cancer
Background Dermatofibrosarcoma protuberans (DFSP) has a high recurrence rate after resection. Because of the lack of specific manifestations, recurrent DFSP is easily misdiagnosed as post-resection scar.
Xia Gong, Jia Li, Angang Ding, Jiaxin Zuo, Yamin Rao, Jun Chen, Ping Xiong   +6 more
doaj   +2 more sources

MRI-Based Surgical Margin Assessment in Dermatofibrosarcoma Protuberans: Correlation With Pathological Extent. [PDF]

J Dermatol
ABSTRACT Dermatofibrosarcoma protuberans (DFSP) is a locally aggressive cutaneous tumor characterized by infiltrative growth and a high risk of local recurrence if incompletely excised. Although Mohs micrographic surgery is recommended, wide local excision (WLE) remains widely used in clinical practice; however, the clinical utility of preoperative ...
Kito M, Iwaya M, Omodaka T, Yuzuriha S, Okamoto M, Tanaka A, Takazawa A, Ideta H, Taruta D, Nemoto K, Aoki K, Takahashi J.   +11 more
europepmc   +2 more sources

Angiogenic and Stromal Remodeling Associated With Aggressive Fibrosarcomatous Dermatofibrosarcoma Protuberans [PDF]

Cancer Sci
FS‐DFSP exhibits coordinated angiogenic and stromal remodeling characterized by immature vascular features, CAF accumulation, and enhanced macrophage infiltration. VEGFA, CCL2, and CXCR4 may contribute to this tumor‐promoting microenvironment. ABSTRACT Although collagen type 1 alpha 1 (COL1A1)–platelet‐derived growth factor B‐chain (PDGFB) gene fusion ...
Shiraishi S, Iwasaki T, Takigawa K, Kawaguchi K, Sonoda H, Miyawaki K, Tomonaga T, Mori T, Endo M, Kato K, Nakashima Y, Oda Y.   +11 more
europepmc   +2 more sources

A 10-year Review of Surgical Management of Dermatofibrosarcoma Protuberans [PDF]

, 2020
Background: Dermatofibrosarcoma protuberans (DFSP) is a rare skin cancer. Standard treatment in the UK is either wide local excision (WLE) or Mohs micrographic surgery (MMS).
Marsden, J, Durack, A, Gran, S., Craythorne, E, Harwood, CA, Matin, R N, Gran, S, Craythorne, E., Gardiner, Md, ?, ?, Harwood, C A, Gardiner, M. D., Proby, CM, DFSP Collaborators, Proby, C. M., Marsden, J., Durack, A., Jain, A, Matin, RN, Jain, A., Gardiner, MD.   +20 more
core   +2 more sources

Dermatofibrosarcoma Protuberance (DFSP) of Parotid Gland – A Case Report [PDF]

, 2022
Dermatofibrosarcoma protuberans (DFSP) is a rare slow-growing low-grade dermal sarcoma typically found on the chest or proximal extremities. Uncommon sites include the head, face, and neck area.
Not Applicable
core   +1 more source

Atrophic Pigmented Dermatofibrosarcoma Protuberans: A Case Report and Literature Review

Frontiers in Oncology, 2021
Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma characterized by the proliferation of spindle cells arranged in a storiform pattern. Here we report a case of DFSP presenting as a bluish-black atrophic plaque.
Juan Bai, Bin Liu, Taoming Liu, Jianjun Qiao, Hong Fang   +4 more
doaj   +1 more source

Autoclosing Excision Design for Dermatofibrosarcoma Protuberans in Slow Mohs Surgery [PDF]

Clin Case Rep
ABSTRACT In DFSP treated with slow Mohs surgery, first‐stage planning is critical given delayed histologic results. The pinch test allows intraoperative assessment of skin mobility, enabling margin tailoring beyond the standard 1–1.3 cm when laxity permits, while preserving primary closure.
Lupon E, Ivan I, Camuzard O, Gandolfi S, Gangloff D.   +4 more
europepmc   +2 more sources

Comprehensive analysis of transcriptome characteristics and identification of TLK2 as a potential biomarker in dermatofibrosarcoma protuberans

Frontiers in Genetics, 2022
Background: Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous sarcoma characterized by local invasion and recurrence. RNA sequencing (RNA-seq) allows the qualification of cellular RNA populations and provides information on the transcriptional ...
Xiao Zhang, Di Sun, Haiyan Zheng, Yamin Rao, Yuqi Deng, Xiao Liang, Jun chen, Jun Yang   +7 more
doaj   +1 more source