Results 201 to 210 of about 29,304 (266)

Characterization of Lysosomal Hydrolases and Transporters and Their Age‐Dependent Variability: Relevance to Drug Metabolism and Transport of Small Molecule and Biologic Drugs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Lysosomes play a key role in the accumulation, catabolism, and transport of endogenous and exogenous metabolites and proteins and are involved in drug metabolism and prodrug activation. However, the protein abundance and interindividual variability of lysosomal drug‐metabolizing enzymes and transporters (DMETs) remain underexplored.
Darshak Gadara   +20 more
wiley   +1 more source

Efficiency and Perceptions in Public CSR: An Integrated Efficiency–Perception Analysis of Spanish Defence Delegations

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Public organisations often experience a discrepancy between improvements in technical efficiency and stakeholders' perceptions of integrity and performance. This study analyses the mechanisms that may underlie this efficiency–perception discrepancy in Spanish Defence Delegations during 2020–2023.
José Solana‐Ibáñez   +1 more
wiley   +1 more source

Cumulative Cytological Assessment of Repeated Non‐Diagnostic Thyroid Fine Needle Aspirations: A Novel Approach to Reduce Diagnostic Uncertainty

open access: yesDiagnostic Cytopathology, EarlyView.
ABSTRACT Purpose Fine needle aspiration (FNA) is the primary diagnostic tool for evaluating thyroid nodules. However, 10%–21% of FNAs yield non‐diagnostic (ND) results (Bethesda category I). Repeated ND findings occur in 25%–67.5% of cases, creating diagnostic uncertainty and increased healthcare costs.
Shiri Damti Geva   +7 more
wiley   +1 more source

Making Sense of the Bioeconomy: A Critical Analysis of EU Policy Narratives and Responses

open access: yesEnvironmental Policy and Governance, EarlyView.
ABSTRACT The bioeconomy has become an increasingly popular concept in European Union (EU) policy, promising sustainable growth, job creation, and reduced environmental impacts. Yet its meaning remains contested, ambiguous, and politically charged. This study critically examines how EU bioeconomy policy narratives prior to 2025 construct this concept ...
Elena Zepharovich   +4 more
wiley   +1 more source

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