Results 71 to 80 of about 25,184 (257)

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

A Serial Feeding Network with Defected Ground Structure

Leida xuebao, 2014
A novel serial feeding network with Defected Ground Structure (DGS) is proposed in this paper. The stripline feed network uses multilayer board laminated structure and DGS on the surface.
Xi Song-tao, Wu Xiao-po
doaj   +1 more source

Mitigating Cancer Therapy–Related Cognitive Impairment by Targeted Activation of Undruggable Phosphatase

Advanced Science, EarlyView.
An RVG‑engineered exosomal saRNA delivery system (RVG‑EVs‑saPtpro) effectively targets and activates hippocampal PTPRO, functioning as a “molecular brake” to alleviate cancer therapy‑related cognitive impairment (CTRCI) by enhancing neuronal survival, neurogenesis, and synaptic plasticity.
Zhimeng Yao, Yuhua Meng, Huanyi Li, Yinhui Jiang, Xiaona Lin, Mengyuan Hu, Qing Liu, Xiaofu Qiu, Hongzheng Ren, Yunlong Pan, Bin Pan, Zexiong Guo, Shuyao Zhang, Dianzheng Zhang, Li Yang, Shegan Gao, Weijing Deng, Jianfan Chen, Hao Zhang   +18 more
wiley   +1 more source

Defected Ground Structure: Fundamentals, Analysis, and Applications in Modern Wireless Trends

International Journal of Antennas and Propagation, 2017
Slots or defects integrated on the ground plane of microwave planar circuits are referred to as Defected Ground Structure. DGS is adopted as an emerging technique for improving the various parameters of microwave circuits, that is, narrow bandwidth ...
Mukesh Kumar Khandelwal, Binod Kumar Kanaujia, Sachin Kumar   +2 more
doaj   +1 more source

HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

EYE-CLOSED4^ (DGS) [PDF]

This video shows one variant of the German Sign Language (DGS) sign for to close the eyes. For more information, see the sign type EYE-CLOSED4^ in the Public DGS Corpus (https://doi.org/10.25592/dgs.corpus-3.0-type-86952)
Sarah Schwarzenberg, Annika Herrmann, Ivo Weber   +2 more
core   +3 more sources

Analysis of Optimal Deployment of Several DGs in Distribution Networks Using Plant Propagation Algorithm

IEEE Access, 2020
In recent years, the substantial upsurge of electricity demand has directly impacted the performance of the distribution networks concerning the active power losses and voltage drops.
Asad Waqar, Umashankar Subramaniam, Kiran Farzana, Rajvikram Madurai Elavarasan, Habib Ur Rahman Habib, Muhammad Zahid, Eklas Hossain   +6 more
doaj   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Dispositional Greed Scale: evidências de sua estrutura interna e parâmetros dos itens

Psico-USF, 2019
Resumo Este estudo objetivou conhecer as evidências da estrutura interna da Dispositional Greed Scale (DGS) e os parâmetros de seus itens. Contou-se com a participação de 338 pessoas com média de idade de 26,5 anos (DP = 8,18), que responderam a DGS e ...
Leogildo Alves Freires, Gleidson Diego Lopes Loureto, Maria Gabriela Costa Ribeiro, Layrtthon Carlos de Oliveira Santos, Valdiney Veloso Gouveia   +4 more
doaj   +1 more source

MASH Background Confers Enhanced Disease Susceptibility and Acetaminophen Toxicity in iPSC‐Derived Liver Organoids

Advanced Science, EarlyView.
This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha, Ashwani Kumar Gupta, Nate Schmidt, Richard M. Green, John G. Purdy, Jason A. Wertheim   +5 more
wiley   +1 more source