Results 41 to 50 of about 172,429 (327)

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Blockchain-Driven E-Voting: Enhancing Security and Integrity with Smart Contracts

JISR on Computing
In any democratic electoral system the fundamental right of every eligible citizen is to vote in order to elect the desired representative. However minimal efforts have been made to improve the voting mechanism.
Urooj Waheed, Muhammad Ahsan Khan, Yusra Mansoor, Huma Jamshed, Ahmad Hussain   +4 more
doaj   +1 more source

Sense-Making/Giving during the COVID-19 Crisis: A Multi-Method Study of Health Podcasting in Australia and the U.S.

Lingue Culture Mediazioni, 2023
Sense-making and sense-giving represent an issue of communication (Weick et al. 2005). The former is associated with emotional processes of crisisassessment and cognitive processes of justifying and seeking social acceptance for decisions (Søderberg and ...
Rosita Belinda Maglie, Matthew Josef Groicher   +1 more
doaj   +1 more source

Revealing How Acid Sites Enhance the Electrocatalytic Glycerol Oxidation Performance on Pt Loaded Zeolite‐Carbon Composite Materials

Advanced Materials, EarlyView.
In the work reported herein, the catalytic effects of acid sites on electrocatalytic glycerol oxidation reaction are investigated by using a novel catalytic material system that integrates Pt metal sites with acidic Al sites. Abstract The catalytic role and function of acid sites in solid acid catalysts, such as zeolites, are well understood in the ...
Ju Ye Kim, Sunjae No, Jinwoo Hwang, Mi Yoo, Hakju Lee, Youngbi Kim, Youngmin Kim, Yong Tae Kim, Jeong‐Chul Kim, Jeong Woo Han, Kyoungsoo Kim, Hyung Ju Kim   +11 more
wiley   +1 more source

The impact of fish oil fatty-acids on post-prandial vascular reactivity. [PDF]

, 2014
Progressive loss of vascular reactivity and increased vascular tone with age are being increasingly recognised as significant cardiovascular disease (CVD) risk factors.
Mcmanus, Sean
core  

A GLUTAMATE CYSTEINE LIGASE Gene StGSH1 Regulated by StERF10 Enhanced Glutathione Accumulation and Adaptation to Low Phosphorus Stress in Potato

Advanced Science, EarlyView.
The StERF10‐StGSH1 module coordinates glutathione (GSH) biosynthesis under low‐phosphorus stress. The low‐phosphate‐induced AP2/ERF transcription factor StERF10 directly activates the transcription of StGSH1 and enhances GSH accumulation. Consequently, GSH scavenges reactive oxygen species and provides sulfur for sulfolipid synthesis, facilitating the ...
Xiaocheng Tian, Mingjun Li, Xiaojia Huang, Markus Wirtz, Xiaohui Zheng, Shilong Fan, Jiang Tian, Shaoqun Liu, Zhonghua Liu, Hongbo Zhao   +9 more
wiley   +1 more source

Fish Oil Supplementation Reduces Markers of Oxidative Stress But Not Muscle Soreness After Eccentric Exercise [PDF]

, 2014
Peer ...
Chappell, Andrew John, Gray, Patrick, Gray, Stuart Robert, Jenkinson, Alison McEwan, Thies, Frank   +4 more
core   +1 more source

Activating the Osteoblastic USP26 Pathway Alleviates Multi‐Organ Fibrosis by Decreasing Insulin Resistance

Advanced Science, EarlyView.
The loss of Ubiquitin Specific Peptidase 26 (USP26) in osteoblasts results in decreased bone formation, as well as multi‐organ fibrosis associated with insulin resistance (IR). Mechanistically, the absence of USP26 reduces glycolysis and lactate accumulation, leading to decreased histone H3 lysine 18 lactylation (H3K18LA) in the promoter region of KH ...
Jiyuan Tang, Wenkai Ye, Liang He, Zhou Dan, Leilei Chang, Zijie You, Yuanyue Jiang, Guoqing Tang, Lianfu Deng, Changwei Li   +9 more
wiley   +1 more source

Relationship of Optimism Biases and Burnout with Work Stress in Mental Health Professionals: The Mediating Role of Psychological Well-being and Moderating Role of Resilience

Sustainable Business and Society in Emerging Economies
Purpose: This research aims to find out the relationship between optimism biases, burnout, and work stress with psychological well-being as a mediator and resilience as a moderator of mental health professionals from age 18 to 50.
Qintar Ul Firdous, Azam Anwar Khan
doaj   +1 more source