Results 51 to 60 of about 17,491 (180)

How Much Evidence Is Enough? Research Sponsor Experiences Seeking Regulatory Acceptance of Digital Health Technology-Derived Endpoints

open access: yesDigital Biomarkers, 2023
Introduction: Digital health technologies (DHTs) provide opportunities for real-time data collection and assessment of patient function. However, use of DHT-derived endpoints in clinical trials to support medical product labelling claims is limited ...
Brian Perry   +6 more
doaj   +1 more source

Annual Banned‐Substance Review 18th Edition—Analytical Approaches in Human Sports Drug Testing 2024/2025

open access: yesDrug Testing and Analysis, EarlyView.
New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley   +1 more source

Matlab Code for the Discrete Hankel Transform

open access: yesJournal of Open Research Software, 2017
Previous definitions of a Discrete Hankel Transform (DHT) have focused on methods to approximate the continuous Hankel integral transform without regard for the properties of the DHT itself.
Natalie Baddour, Ugo Chouinard
doaj   +1 more source

Statistical Discrimination of Urinary Steroid Biomarkers in the Athlete Biological Passport: A Novel Approach to an Abnormal Steroid Profile Score (ASPS)

open access: yesDrug Testing and Analysis, EarlyView.
The study developed a single Abnormal Steroid Profile Score (ASPS) to improve interpretation of the Athlete Biological Passport steroid module. Using Bayesian modelling and logistic regression, biomarker patterns from laboratory and doping control data successfully discriminated between doped and clean individuals, with improved classification ...
James G. Hopker   +3 more
wiley   +1 more source

EVIDÊNCIAS DA CONECTIVIDADE HIDRÁULICA ENTRE OS SISTEMAS AQÜÍFEROS SERRA GERAL E GUARANI NO ESTADO DE MATO GROSSO DO SUL E ASPECTOS AMBIENTAIS CORRELACIONADOS

open access: yesRevista Águas Subterrâneas, 2007
Relações de fluxo das águas subterrâneas entre as duas unidades hidroestratigráficas da Bacia Sedimentar do Paraná, o Sistema Aqüífero Serra Geral (SASG) e o Sistema Aqüífero Guarani (SAG), são conhecidas a partir de evidências observadas nos estados do ...
Giancarlo Lastoria   +4 more
doaj  

Liraglutide improves hypertension and metabolic perturbation in a rat model of polycystic ovarian syndrome.

open access: yesPLoS ONE, 2015
Polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, with a prevalence of 5-8%. Type 2 diabetes and cardiovascular disease (CVD) are its long-term complications.
Vanessa Hoang   +3 more
doaj   +1 more source

Detection of focal impaired awareness seizures using a biometric shirt

open access: yesEpilepsia Open, EarlyView.
Abstract Objective In recent years, seizure detection using wearable technology has gained significant attention in research. Most studies, however, have focused on detecting generalized or focal to bilateral tonic–clonic seizures. This study evaluates the feasibility of using a biometric shirt to detect focal impaired awareness seizures (FIAS) by ...
Jérôme St‐Jean   +6 more
wiley   +1 more source

Adding query privacy to robust DHTs [PDF]

open access: yesProceedings of the 7th ACM Symposium on Information, Computer and Communications Security, 2012
Interest in anonymous communication over distributed hash tables (DHTs) has increased in recent years. However, almost all known solutions solely aim at achieving sender or requestor anonymity in DHT queries. In many application scenarios, it is crucial that the queried key remains secret from intermediate peers that (help to) route the queries towards
Backes, Michael   +3 more
openaire   +3 more sources

Evaluating the Endocrine‐Disrupting and Oxidative Stress Potential of a 50‐Component Human‐Relevant Complex Chemical Mixture Using In Vitro Tests

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Humans are chronically exposed to mixtures of environmental contaminants. Exposure to endocrine‐disrupting chemicals (EDCs) contributes to increased health impairment observed globally. This study aimed to evaluate the endocrine‐disruptive and oxidative stress potential of a human‐relevant, complex chemical mixture in vitro.
Josefin Engelhardt   +5 more
wiley   +1 more source

Endocrine Response of Hybrid Rabbits of Different Ages and Under Two Environmental Temperature Conditions [PDF]

open access: yesTropicultura, 1997
The trial was carried out on 44 hybrid male rabbits in order to study the plasma levels of testosterone (T), dihydrotestosterone (DHT), cortisol (C), triiodothyronine (T3) and thyroxine (T4) in relation to age (71 vs 85 days) and environmental ...
Chiericato, GM.   +4 more
doaj  

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