Results 61 to 70 of about 17,491 (180)

Effects of dihydrotestosterone on osteoblast activity in curdlan-administered SKG mice and osteoprogenitor cells in patients with ankylosing spondylitis

open access: yesArthritis Research & Therapy, 2020
Background Ankylosing spondylitis (AS) is characteristically male-predominant, and progressive spinal ankylosis affects male patients more severely; however, the hormonal effects in males with AS are poorly understood.
Sungsin Jo   +8 more
doaj   +1 more source

Effects of testosterone and high‐dose anabolic steroids on orthodontic‐induced bone remodeling and root resorption: An animal study

open access: yesJournal of Periodontology, EarlyView.
Abstract Background This study investigates the impact of disruptions in testosterone levels on bone remodeling, root resorption, and periodontal ligament (PDL) during orthodontic tooth movement (OTM) in a pubertal male rat model. Methods Testosterone deficiency was induced through orchiectomy, and the anabolic‐androgenic steroid (AAS, testosterone ...
Caio Luiz Bitencourt Reis   +11 more
wiley   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu   +5 more
wiley   +1 more source

Sybil-Resistant DHT Routing [PDF]

open access: yes, 2005
Distributed Hash Tables (DHTs) are very efficient distributed systems for routing, but at the same time vulnerable to disruptive nodes. Designers of such systems want them used in open networks, where an adversary can perform a sybil attack by introducing a large number of corrupt nodes in the network, considerably degrading its performance.
George Danezis   +3 more
openaire   +1 more source

Exploring the Gut‐Prostate Axis: Microbial Signatures Linked to Prostate Volume and Bladder Function

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is a common urologic condition in aging men, often linked to systemic inflammation and metabolic dysfunction. Emerging evidence suggests that the gut microbiome may contribute to prostate health and disease.
Jonathan Surber   +12 more
wiley   +1 more source

Alteration of the hypothalamic-pituitary-gonadal axis in estrogen- and androgen-treated adult male leopard frog, Rana pipiens

open access: yesReproductive Biology and Endocrinology, 2005
Background Gonadal steroids, in particular 5 alpha-dihydrotestosterone (DHT) and 17 beta-estradiol (E2), have been shown to feed back on the hypothalamic-pituitary-gonadal (HPG) axis of the ranid frog.
Jones Jeremy T   +3 more
doaj   +1 more source

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Anti‐Globalization Dynamics and Africa's Structural Transformation: Identifying Avoidable Environmental Degradation Thresholds

open access: yesSustainable Development, EarlyView.
ABSTRACT This study pursues a dual objective. First, it investigates the unconditional impact of anti‐globalization on structural transformation in Africa. Second, it explores how environmental degradation interacts with anti‐globalization to influence structural transformation. The analysis focuses on 52 African countries over the period 2005–2023. To
Simplice A. Asongu, Ekene ThankGod Emeka
wiley   +1 more source

Neuroprotection by dihydrotestosterone in LPS-induced neuroinflammation

open access: yesNeurobiology of Disease, 2020
Microglia-induced neuroinflammation plays a vital role in the etiology and progression of neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and multiple sclerosis. The neuroprotective role of androgens, including testosterone
Lei Yang   +6 more
doaj   +1 more source

LMS-based DHT analyser

open access: yesElectronics Letters, 1988
A least-mean-square (LMS) adaptive algorithm for calculating the discrete Hartley transform (DHT) is presented. The transform kernel of the DHT serves as the input vector and the input signal to be analysed is regarded as the ‘desired response’ for the adaptive process. For a proper choice of convergent factor, i.e. u = 1/2, the ‘LMS DHT analyser’ will
J.-C. Liu, T.-P. Lin
openaire   +1 more source

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