Diabetes Complications and Comorbidities as Risk Factors for MACE in People With Type 2 Diabetes and Their Development Over Time: A Danish Registry-Based Case-Control Study. [PDF]
Bech AA+4 more
europepmc +1 more source
This study introduces a novel therapeutic approach that employs a conductive hydrogel (HEPP) responsive to near‐infrared light, pH levels, and reactive oxygen species. Its goal is to enhance the healing environment affected by elevated glucose levels, insufficient oxygen, and bacterial infections in diabetes‐related wounds.
Tao Zhang+4 more
wiley +1 more source
Sex-Specific Blood Pressure Trajectories and Cardiovascular Disease in Type 1 Diabetes: 32-Year Follow-up of the Pittsburgh Epidemiology of Diabetes Complications Cohort. [PDF]
Miller RG, Orchard TJ, Costacou T.
europepmc +1 more source
Ultrasound (US)‐treated nanocomposite ‘lever’ hydrogels reprogrammed wound reactive oxygen species (ROS) levels and promoted wound healing in infected diabetic foot ulcers. Abstract Diabetic foot ulcers (DFUs) are a complex mixture of neuropathy, peripheral arterial disease, and infection, where excessive reactive oxygen species (ROS) exacerbates ...
Yuting Shen+16 more
wiley +1 more source
The m6A-ncRNAs axis in diabetes complications: novel mechanism and therapeutic potential. [PDF]
Yu S+6 more
europepmc +1 more source
FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li+11 more
wiley +1 more source
Inflammation in diabetes complications: molecular mechanisms and therapeutic interventions. [PDF]
Zhao L+8 more
europepmc +1 more source
This study reveals that Testosterone–Androgen Receptor signaling delays elderly male bone destruction by upregulation of the osteoblastic extracellular tenascin‐C (TNC). The osteoprotective effect of fibrinogen C‐terminus of TNC is demonstrated in male osteoporotic mice model that osteoblast‐specific Ar‐knockout, potentially via inhibition of ...
Yong Xie+8 more
wiley +1 more source
Type 2 diabetes complications in ethnic minority compared with European host populations: a systematic review and meta-analysis. [PDF]
Beulens JWJ+9 more
europepmc +1 more source