Results 181 to 190 of about 634,910 (313)

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Impact of Islet Transplantation on Diabetes Complications and Mortality in Patients Living With Type 1 Diabetes. [PDF]

Diabetes Care
Perrier Q, Jambon-Barbara C, Kessler L, Villard O, Buron F, Guerci B, Borot S, Roustit M, Berishvilli E, Rakotoarisoa L, Vantyghem MC, Morelon E, Renard E, Besch C, Berney T, Benhamou PY, Lablanche S, GRAGIL Network .   +17 more
europepmc   +1 more source

Histone deacetylases and inhibitors in diabetes mellitus and its complications

Wang Li, Yuning Bai, Zhengmin Cao, Ziwei Guo, Yanjie Lian, Pan Liu, Yixian Zeng, Wenliang Lyu, Qiu Chen   +8 more
openalex   +1 more source

Dependence of Retinopathy (and other Complications) on Glycaemic Control and on Weight over 5/10 Years from Diagnosis of Type II Diabetes [PDF]

, 1996
Barbara J. Boucher, J Tsoumanis, Kate Noonan, John Holmes   +3 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Deep learning for enhanced prediction of diabetic retinopathy: a comparative study on the diabetes complications data set. [PDF]

Front Med (Lausanne)
Gong W, Pu Y, Ning T, Zhu Y, Mu G, Li J.
europepmc   +1 more source

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

Advanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang, Zhichao Li, Tianci Hu, Qinyao Li, Linwei Zhang, Xinyue Mei, Xiao Qi, Sheng Liu, Weijie Kong, Jiesi Luo, Anguo Wu, Feihong Huang, Sirui Li, Shuang Dai, Chunxiang Zhang, Rong Li, Jianming Wu   +16 more
wiley   +1 more source

Letter to the Editor in Response to 'A prediction model for diabetes complications using the Kokuho Database and its application to public health services in Japan'. [PDF]

J Diabetes Investig
Le Y, Xu F, Xu Q.
europepmc   +1 more source

Diabetes: complications and the economic burden

, 2014
Danny Meetoo
openalex   +2 more sources

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source