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Pregnancy complicating diabetes
The American Journal of Medicine, 1945Recent published reports indicate that obstetric and diabetic clinics now agree that whereas the maternal mortality in diabetic pregnancies has been low fetal mortality has been high. The past fetal mortality rates have ranged from 30 to 60 per cent, depending on the length of pregnancy observed.
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Microvascular complications of diabetes
Endocrinology and Metabolism Clinics of North America, 2004Several theories of the pathogenesis of microvascular complications of diabetes (diabetic retinopathy, nephropathy, and neuropathy) have been proposed: (1) generation of reactive oxygen species and oxidative stress, (2) activation of polyol pathway, (3) formation of advanced glycation end products, (4) induction of flux through the hexosamine pathway, (
Zhiheng, He, George L, King
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Journal of Wound Care, 1997
A case study describing the difficulties encountered by a joint vascular and diabetic foot-care team in the management of a patient with a late ...
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A case study describing the difficulties encountered by a joint vascular and diabetic foot-care team in the management of a patient with a late ...
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Complication in diabetic nephropathy
Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 2016Diabetic kidney disease is the most common cause of chronic kidney disease, leading to end-stage renal disease (ESRD) and premature death. In addition, it negatively affects a patient's quality of life and social environment, and poses a burden on national health care budgets.
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Prevention of diabetes complications
Clinical Cornerstone, 1998Basic and clinical research findings have led to an increased understanding about diabetes and its complications. Therapeutic approaches are now based not only on predicted effects from epidemiologic, correlative, or retrospective analyses, but often on prospective intervention trials comparing a new form of therapy to the standard methods.
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Orthopedic complications in diabetes
Bone, 2016Diabetes is associated with a number of lower extremity orthopedic conditions and complications including fractures, Charcot neuroarthropathy, plantar ulcers, and infection. These complications are of significant clinical concern in terms of morbidity, mortality, and socioeconomic costs. A review of each condition is discussed, with particular emphasis
Daniel J. Gehling +2 more
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The genetics of diabetic complications
Nature Reviews Nephrology, 2015The rising global prevalence of diabetes mellitus is accompanied by an increasing burden of morbidity and mortality that is attributable to the complications of chronic hyperglycaemia. These complications include blindness, renal failure and cardiovascular disease. Current therapeutic options for chronic hyperglycaemia reduce, but do not eradicate, the
Emma, Ahlqvist +3 more
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Complications of the Diabetic Foot
Endocrinology and Metabolism Clinics of North America, 2013The diabetic foot is at high risk for complications because of its role in ambulation. Peripheral neuropathy and peripheral vascular disease can lead to chronic foot ulcers, which are at high risk for infection, in part attributable to areas of high pressure caused by lack of tolerance of the soft tissue and bone and joint deformity. If left untreated,
Paul J, Kim, John S, Steinberg
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Preventing diabetes complications
Internal Medicine JournalThe key aim of diabetes management is to prevent complications, which are a major cause of morbidity and mortality. At an individual level, people with diabetes are less likely than they were several decades ago to experience classical macrovascular and microvascular complications as a result of improvements in modifiable cardiovascular risk factors ...
Sophie Templer, Sarah Abdo, Tang Wong
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ACE2 and Diabetic Complications
Current Pharmaceutical Design, 2007Angiotensin converting enzyme (ACE) is a key enzyme in the renin angiotensin system (RAS) and converts angiotensin (Ang) I to the vasoconstrictor Ang II, which is thought to be responsible for most of the physiological and pathophysiological effects of the RAS.
Rachael G, Dean, Louise M, Burrell
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