Results 281 to 290 of about 154,081 (362)

Cancer therapy‐related cardiotoxicity is associated with distinct alterations of the myocardial lipidome

open access: yesEuropean Journal of Heart Failure, EarlyView.
Lipidome changes in anthracycline‐induced cardiotoxicity (AIC). Aims Anthracyclines are key components of various chemotherapy regimens, but their clinical utility is limited by severe cardiotoxic side effects. Previous studies have suggested that anthracycline‐induced cardiotoxicity (AIC) may be driven by alterations in myocardial lipid metabolism ...
Vera M. Braun   +6 more
wiley   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

PDB6: EVALUATION OF CLINICAL AND DEMOGRAPHIC FACTORS ASSOCIATED WITH DIABETIC FOOT ULCER TREATMENT COSTS

open access: bronze, 2000
SW Wade   +5 more
openalex   +1 more source

Bonding of Hydrogel to Biometal Surfaces: Principles, Methods and Applications

open access: yesExploration, EarlyView.
This article reviews the research progress of hydrogel coatings on biometal surfaces, focusing on biometal surface pretreatment methods, hydrogel‐biometal bonding methods, and applications of hydrogel coatings on biometal surfaces. The article also discusses potential future applications of hydrogel coatings on biometal surfaces to provide a broader ...
Yujie Zhou   +10 more
wiley   +1 more source

Natural products in the treatment of diabetic foot infection. [PDF]

open access: yesEur J Med Res
Nazari M, Shokoohizadeh L, Taheri M.
europepmc   +1 more source

Engineered Exosome‐Based Senolytic Therapy Alleviates Stroke by Targeting p21+CD86+ Microglia

open access: yesExploration, EarlyView.
We identified a harmful immune cell type, p21+CD86+ microglia, driving post‐stroke inflammation and developed a targeted exosome‐based therapy (Que@micro‐Exo) to eliminate these cells. This innovative treatment reduced inflammation, alleviated brain damage, and improved recovery in stroke models, offering a promising strategy for stroke and other ...
Jialei Yang, Shipo Wu, Miao He
wiley   +1 more source

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