Results 191 to 200 of about 2,351,607 (276)

Cost‐effectiveness of investing in earlier access to diabetic foot services: A multi‐centre pre‐post study

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims We evaluated the cost‐effectiveness of implementing a novel funding model to incentivise earlier access of patients with diabetes‐related foot disease (DFD) to diabetic foot services (DFS). Methods In this multi‐centre pre‐post study, we compared the cost, quality‐adjusted life year (QALY) and clinical outcomes of patients with diabetes ...
Son Nghiem   +10 more
wiley   +1 more source

Perioperative glycaemic profiles in Aboriginal and Torres Strait Islander people with diabetes mellitus

open access: yesDiabetic Medicine, EarlyView.
This large multicentre retrospective cohort study in Australia revealed that despite being younger and having greater preoperative comorbidity and higher HbA1c levels, Aboriginal and Torres Strait Islander adults with diabetes mellitus demonstrate higher rates of perioperative hypoglycaemia, but otherwise comparable markers of glycaemic variability and
Katerina Flabouris   +5 more
wiley   +1 more source

Microbiological characterization of neuropathic diabetic foot infection: a retrospective study at a Portuguese tertiary hospital. [PDF]

open access: yesBMC Infect Dis
Gonçalves J   +14 more
europepmc   +1 more source

Early sodium‐glucose co‐transporter 2 inhibitor initiation is associated with improved cardiovascular outcomes in type 2 diabetes and acute coronary syndrome

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Sodium‐glucose co‐transporter 2 inhibitors have demonstrated cardiovascular benefits in individuals with type 2 diabetes mellitus, but the optimal timing of initiation in those with acute coronary syndrome is not known. This study aims to assess if early therapy at discharge is superior to delayed or no therapy in reduction in major ...
Muhammad Usman Shah   +7 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs   +9 more
wiley   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

open access: yesThe FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy