Results 51 to 60 of about 2,351,607 (276)
Bacterial Diversity and Antibiotic Resistance in Patients with Diabetic Foot Osteomyelitis
Antibiotics, 2023 This study analysed the bacterial diversity, antibiotic susceptibility, and resistance in patients with complications of diabetic foot osteomyelitis (DFO).
Francisco Javier Álvaro-Afonso +5 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals that during skeletal aging, bone marrow adipocyte‐derived sDPP4 primes STING signaling in macrophages. In combination with mitochondrial DNA, this signaling activates CD38 and depletes local NAD+/NMN, thereby impairing osteogenesis.
Zhichao Li +12 more
wiley +1 more source
Hepatology, EarlyView., 2022 Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario +12 more
wiley +1 more source
Diabetic foot infection: A critical complication
International Wound Journal, 2018 The number of people in the world with diabetes has nearly quadrupled in the past 40 years. Current data show that 25% of these diabetics will develop a foot ulcer in their lifetime and that the cost of care for a diabetic foot ulcer (DFU) is over twice that of any other chronic ulcer aetiology.
Hurlow, Jennifer J. +3 more
openaire +4 more sources
Advanced Science, EarlyView.A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang +10 more
wiley +1 more source
Advanced Science, EarlyView.After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi +16 more
wiley +1 more source
The Problems and Cost-Effectiveness Analysis of Diabetic Foot Infections
Endocrinology Research and Practice, 2012 Objective: Hospitalization in patients with diabetic foot infection usually increases costs due to required long-term medical treatments and surgical managements.
Mustafa Sait Gönen +10 more
doaj +2 more sources
Kidney Research and Clinical Practice, 2013 Background: Diabetic patients are predisposed to foot infections because of vascular insufficiency and peripheral neuropathy. Diabetic foot infection is a common cause of mortality and lower extremity amputations (LEAs) in patients with chronic kidney ...
Sang Jin Lee +8 more
doaj +1 more source
Antimicrobial dressings for treating local infection in patients with diabetic foot ulcers
, 2018 Infection in diabetic foot ulcers puts patients at risk of hospitalisation and amputation. Microorganisms populate chronic wounds on a continuum from non-pathological surface contamination to local infection and/or deep compartment infection.
Ivory, John D. +2 more
core +1 more source
Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism
Advanced Science, EarlyView.Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He +7 more
wiley +1 more source