Results 201 to 210 of about 1,719,974 (229)

Validation of the fullPIERS model for predicting severe maternal outcomes in preeclampsia in five Brazilian centers

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 174-181, October 2026.
Abstract Objective The objective of this study is to validate the fullPIERS (Pre‐eclampsia Integrated Estimate of Risk) prognostic model in a large, multicenter cohort of Brazilian women with preeclampsia and to determine the optimal cutoff for clinical application in the Brazilian context.
Pedro do Valle Teichmann, José Paulo Siqueira Guida, Maria Laura Costa, Leila Katz, Melania Maria Amorim, Jussara Mayrink, Giorgio Tondello, Sergio Hofmeister de Almeida Martins Costa, José Geraldo Lopes Ramos   +8 more
wiley   +1 more source

The Clinical Characteristic and Prognostic Value of Frailty in Elderly COPD Patients

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background and Objective Frailty, as one of the extrapulmonary comorbidities of chronic obstructive pulmonary disease (COPD), is highly prevalent in COPD patients. The primary objective of this research was to assess how frailty influences subsequent exacerbation and augments the predictive capacity of dyspnoea or the exacerbation history ...
Tao Li, Ping Zhang, Qing Song, Cong Liu, Ling Lin, Yuqin Zeng, Ping Chen   +6 more
wiley   +1 more source

Prevalence and Overlap of Malnutrition, Sarcopenia and Related Nutritional Syndromes in a Large Haemodialysis Population

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Chronic kidney disease is a major global health burden linked to malnutrition, sarcopenia and related nutritional syndromes including protein‐energy wasting (PEW)/cachexia and sarcopenic obesity (SO). Data from end‐stage kidney disease (ESKD) populations in Saudi Arabia and the wider Middle East are scarce.
Hanaa Noor, Subhashini Ganesan, Flavia Martinez Cantarutti, Ali Alharbi, Imed Helal, Joanne Reid, Adrian Slee   +6 more
wiley   +1 more source

Surface Electromyographic Characteristics of Lower Limb Muscles in Frail Older Adults With Cardiovascular Disease: A Case–Control Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Frailty predicts poor outcomes in older adults with cardiovascular disease (CVD) and is closely related to neuromuscular dysfunction. Lower limb surface electromyography (sEMG) during walking may capture frailty‐related motor alterations, but its characteristics and discriminative value in older adults with CVD remain unclear.
Pingping Huang, Shiqi Chen, Linjing Wu, Jiahua Li, Rongxiang Zhang, Shufen Liu, Yuan Chen   +6 more
wiley   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

MedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo, Francesco Marocco, Clemens Zwergel, Marco Tripodi, Cecilia Battistelli   +4 more
wiley   +1 more source

Dynamic Changes of Neutrophil Nuclear Membrane CD63 as a Potential Biomarker for Early Adjunctive Diagnosis and Prognostic Evaluation of Sepsis in Critically Ill Patients: A Prospective Cohort Study

MedComm, Volume 7, Issue 10, October 2026.
Here, we report that nuclear membrane CD63 (nmCD63), a marker of targeted nuclear degranulation in neutrophils, represents a novel biomarker for sepsis. In a two‐center prospective cohort with independent external validation, nmCD63 outperforms CRP and PCT for early sepsis diagnosis, with the nmCD63+SOFA combined model reaching an AUC of 0.943.
Xingxin Gao, Min Zhang, Linbin Li, Haihua Lyu, Zhihao Liu, Xucheng Wei, Dehui Li, Yiming Shao   +7 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

MedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma, Xiaoxuan Zhang, Pujun Zhao, Jiaxin Yang, Zhihao Li, Xiaoyang Han, Yixuan Wang, Zhenzhen Cui, Nian Liu, Min Li   +9 more
wiley   +1 more source

Impact of Dietetic Counseling Combined With Digital Tools on Obesity‐Related Indices in Greek Adults: The GATEKEEPER Study

Obesity, Volume 34, Issue 10, Page 1849-1859, October 2026.
ABSTRACT Objective This study aimed to evaluate the effectiveness of dietetic counseling with digital tools on obesity‐related and metabolic outcomes in adults aged ≥ 55 years at high risk for metabolic syndrome (MetS). Methods In this 3‐month randomized controlled trial, 984 adults aged ≥ 55 years with ≥ 1 MetS risk factor were randomized (1:1:1) to ...
Rafaela Makri, Iliana Evangelou, Eva Karaglani, Maria Vlachava, George E. Dafoulas, Ioanna Drympeta, Konstantinos Votis, Eleni I. Georga, Dimitrios I. Fotiadis, Francisco Lupiáñez‐Villanueva, Frans Folkvord, Leandro Pecchia, Giuseppe Fico, Demosthenes Panagiotakos, Odysseas Androutsos, Yannis Manios, GATEKEEPER study (Greek Use Case 1) group, Odysseas Androutsos, Maria Vlachava, Iliana Evangelou, George E. Dafoulas, Alexandra Bargiota, Alexandra Koubitski, Avgi Karaiskou, Glykeria Papagiannopoulou, Thanasis Topis, Thomas Tzekos, Nelly Mylona, Nikos Papaspanos, Yvonne Katergari, Iphigenia Chionidou, Natasha Davitidou, Vivian Katsarou, Yannis Manios, Eva Karaglani, Rafaela Makri, Ilektra Kalogerakou, Alexandros Karagiannis, Ioanna Nakaki, Elpiniki Vlachopoulou, Maria Dimopoulou, Maria Skaltsa, Ioannis Chrysou, Konstantinos Leontiou, Karamperi Katerina, Evangelia Malakou, Anastasios Papalazarou, Elisavet Parlapani, Anastasia Paschaleri, Christos Paximadas, Maria‐Sofia Pelagidou, Kyriakos Reppas, Katerina Tyrothoulaki, Konstantinos Xenos, Spyridon Zarogiannis, Konstantinos Zervos, Ilias Kalamaras, Dimitrios I. Fotiadis, Eleni I. Georga, Daphne N. Katsarou   +59 more
wiley   +1 more source

Association Between the Systemic Inflammatory Response Index and Severe Infection in Patients with Diabetic Foot [Letter]. [PDF]

Diabetes Metab Syndr Obes
Shan Q.
europepmc   +1 more source