Results 21 to 30 of about 33,114 (236)

High Frequency of Diabetic Ketoacidosis in Children with Newly Diagnosed Type 1 Diabetes

Journal of Diabetes Research, 2016
Aim. The aim of this study was to evaluate the incidence of diabetic ketoacidosis in children and adolescents with newly diagnosed type 1 diabetes in 2006-2007 and 2013-2014. Method.
Agnieszka Szypowska, Anna Ramotowska, Monika Grzechnik-Gryziak, Wojciech Szypowski, Anna Pasierb, Katarzyna Piechowiak   +5 more
doaj   +1 more source

Nurses' Performance Regarding Caring of Patient with Diabetic Ketoacidosis [PDF]

Egyptian Journal of Health Care, 2017
Diabetic ketoacidosis is an acute, major, life-threatening complication of diabetes, may be fatal if not treated quickly and appropriately. Nurses' knowledge and practice play important roles in provision of supportive care to decrease morbidity and ...
Asmaa Said Ali, Manal Salah Hassan, Amany Shaaban Ibrahim Ali   +2 more
doaj   +1 more source

Hyperlactatemia in diabetic ketoacidosis

Diabetic Medicine, 2021
AbstractAimsThe study examined the prevalence and degree of lactate elevation in diabetic ketoacidosis, and explored which biochemical abnormalities predicted L‐lactate levels.MethodsWe reviewed episodes of diabetic ketoacidosis from 79 diabetes patients (one episode per patient).
Umesh Masharani, Lisa A. Strycker, Ann A. Lazar, Karin Wu, George A. Brooks   +4 more
openaire   +4 more sources

Severe hypokalaemia in diabetic ketoacidosis: a contributor to central pontine myelinolysis?

Endocrinology, Diabetes & Metabolism Case Reports, 2019
Hypokalaemia at presentation of diabetic ketoacidosis is uncommon as insulin deficiency and metabolic acidosis shifts potassium extracellularly. However, hypokalaemia is a recognised complication of the management of diabetic ketoacidosis as insulin ...
A Chinoy, N B Wright, M Bone, R Padidela
doaj   +1 more source

Successful Treatment of Diabetic Ketoacidosis in a Patient with Insulin Allergy and Coronavirus Disease 2019: A Case Report

Endocrinology Research and Practice, 2022
Diabetic ketoacidosis is a frequent hyperglycemic emergency. During the coronavirus disease 2019 pandemic, researchers showed a higher prevalence of diabetic ketoacidosis and mortality compared with the preceding years.
Doğukan Şenberber, Mehmet Nuri Yakar, Dilan Delibalta, Tevfik Demir, Ali Necati Gökmen   +4 more
doaj  

Recovery time of diabetic ketoacidosis in Africa: Systematic review and meta-analysis

Metabolism Open
Background: Diabetes mellitus is a long-term metabolic disease marked by consistently elevated blood glucose levels. Diabetic ketoacidosis is the medical consequence of diabetes mellitus that has the highest attributed fatality rate.
Tadios Lidetu, Simon Birhanu, Addisu Simachew Asgai, Tsegaamlak Kumelachew Derse, Yideg Abinew, Moges Tadesse, Desalegn Mitiku, Jemberu Chane, Banchamilak Adane, Tadele Kassahun Wudu, Betelhem Mekonnen, Desiyalew Habtamu Tamiru   +11 more
doaj   +1 more source

Clinical Profile of Diabetic Ketoacidosis: A Prospective Study in a Tertiary Care Hospital [PDF]

Journal of Clinical and Diagnostic Research, 2015
Background: Diabetic ketoacidosis, a well-known and major acute metabolic complication classically occurs in young patients with type 1 diabetes. However, it may occur in patients with type 2 Diabetes Mellitus too. Objective: Aim of this study was to
Pankaj Seth, Harpreet Kaur, Maneet Kaur
doaj   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity

Advanced Science, EarlyView.
Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten, Karen Beets, Tessa Schalley, Janne Verreycken, Gayel Duran, Daphne Lintsen, Lisa Schuetz, Xue Zhong, Rinke Nieuwschepen, Melissa Schepers, Brecht Moonen, Jeroen Bogie, Jana Van Broeckhoven, Carlo Heirman, Jurgen Van den Heuvel, Bart Vanderborght, Ismael Varela, Roxanne Nouille, Lotte Jacobs, Jessica Filtjens, Sabah Kasmi, Elise Seynaeve, Veronica Mavrovouna, Jana De Vrieze, Michael A. Brehm, Sandra Maréchal, Sophie Janssens, Florence Lambolez, Niels Hellings, Stefaan De Koker, Bieke Broux   +30 more
wiley   +1 more source

The Reporting Frequency of Ketoacidosis Events with Dapagliflozin from the European Spontaneous Reporting System: The DAPA-KETO Study

Pharmaceuticals, 2022
Dapagliflozin was associated with an increased risk of diabetic ketoacidosis that has led to the European withdrawal of the authorization for the type 1 diabetes. However, it is still used for the treatment of type 2 diabetes.
Gabriella di Mauro, Annamaria Mascolo, Mario Gaio, Concetta Rafaniello, Antonella De Angelis, Liberato Berrino, Giuseppe Paolisso, Francesco Rossi, Annalisa Capuano   +8 more
doaj   +1 more source