Results 111 to 120 of about 50,591 (247)

Role of internal limiting membrane peeling for cases of recalcitrant diabetic macular edema

Kerala Journal of Ophthalmology, 2017
Background/Aims: To investigate the efficacy of internal limiting membrane (ILM) peeling following pars plana vitrectomy for cases of recalcitrant diabetic macular edema in terms of improved visual acuity and reduced central macular thickness (CMT ...
Sujit Das, Rakesh Maggon
doaj   +1 more source

Targeting the NEK7/NLRP3 Inflammasome Axis: Synergistic Protection of Intravitreal MCC950 and Systemic Metformin Against Diabetic Retinopathy in Rats

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Graphical Abstract ABSTRACT Objective Diabetic retinopathy (DR) is characterised by chronic neuroinflammation where the NLRP3 inflammasome plays a pivotal role. This study investigated the therapeutic potential and underlying mechanism of combining systemic metformin (MET) with intravitreal MCC950, a specific NLRP3 inhibitor, in a rodent model of DR ...
Kexuan Ren, Xiaofeng Li
wiley   +1 more source

Driving Innovation: The Impact of National Health Policies on Optometry Research in East Asia

The International Journal of Health Planning and Management, Volume 41, Issue 1, Page 37-46, January 2026.
ABSTRACT This study examines the optometric research landscape in three East Asian countries—China, Japan, and Korea—analysing how research trends align with each country's national health strategies. By evaluating published articles and reviews from national journals between 2006 March 2025, we identify key areas of focus, including paediatric ...
Jihye Ahn, Moonsung Choi
wiley   +1 more source

Letter to the editor: dexamethasone intravitreal implant in the treatment of diabetic macular edema

Clinical Ophthalmology, 2015
John Hall Alimera Sciences Ltd., Aldershot, Hampshire, UK I read “Dexamethasone intravitreal implant in the treatment of diabetic macular edema” published July 2015 by Dugel et al.1This article is very interesting in terms of providing an
Hall J
doaj  

Automatic Segmentation of the Outer and Inner Foveal Avascular Zone by Convolutional Filters

International Journal of Imaging Systems and Technology, Volume 36, Issue 1, January 2026.
ABSTRACT In this paper a new algorithm for segmentation of the foveal avascular zone in optical coherence tomography angiography images of the superficial capillary plexus is presented and evaluated. The algorithm is based on convolutional techniques, and for evaluation it has been compared with a collection of manual segmentations.
Carlos Ruiz‐Tabuenca, Isabel Pinilla, Elvira Orduna‐Hospital, Francisco Javier Salgado‐Remacha   +3 more
wiley   +1 more source

Intravitreal Aflibercept for the Treatment of Diabetic Macular Edema in Routine Clinical Practice: Results from the 24-Month AURIGA Observational Study [PDF]

, 2023
Simone Donati, Chang‐Hao Yang, Xun Xu, Marco Mura, Audrey Giocanti‐Auregan, Hans Hoerauf, Helmut Allmeier, Tobias Machewitz, Kristian T. Johnson, E Santoro, On behalf of the AURIGA study investigators   +10 more
openalex   +1 more source

Association Between Vitamin D Deficiency and the Risk of Diabetic Retinopathy in Patients With Type 2 Diabetes: A Meta‐Analysis

Molecular Genetics &Genomic Medicine, Volume 14, Issue 1, January 2026.
Meta‐analysis of 20 studies (N = 22,408 T2DM patients). Vitamin D deficiency (25[OH]D < 20 ng/mL) associated with 17% higher DR risk: Pooled OR = 1.17, 95% CI: 1.08–1.27, p < 0.001. Mechanistic link: vitamin D regulates retinal inflammation, VEGF suppression, and endothelial protection.
Guoxiao Yu, Chanyuan Cao, Xupeng Shu, Li Yao   +3 more
wiley   +1 more source

Baseline Factors Affecting Changes in Diabetic Retinopathy Severity Scale Score After Intravitreal Aflibercept or Laser for Diabetic Macular Edema [PDF]

, 2017
Dilsher S. Dhoot, Keith Baker, Namrata Saroj, Robert Vitti, Alyson J. Berliner, Carola Metzig, Desmond Thompson, Rishi P. Singh   +7 more
openalex   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Retrospective Study of Diabetic Retinopathy and Macular Edema in Southern Part of Bangladesh

Journal of Ophthalmology
Background. Diabetic mellitus is a vision-threatening disease because it causes diabetic retinopathy worldwide. The main focus of this research is to determine the prevalence and assess the visual outcome in diabetic retinopathy and macular edema ...
Md. Asif Hasan, Sheikh Md. Rabiul Islam, Md. Arif Hayat Khan Pathan   +2 more
doaj   +1 more source