Results 111 to 120 of about 83,999 (309)

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Ultrastructure of neurovascular changes in human diabetic retinopathy [PDF]

, 2018
The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation.
Artico, Marco, Biró, Zsolt, Fehér, János, Micera, Alessandra, Orlando, Maria Patrizia, Scuderi, Gianluca, Spoletini, Maria Luisa, Taurone, Samanta, Turchetta, Rosaria, Varsányi, Balázs   +9 more
core   +1 more source

Validation of a deep learning model for the automated detection and quantification of cystoid macular oedema on optical coherence tomography in patients with retinitis pigmentosa

Acta Ophthalmologica, EarlyView.
Abstract Purpose Accurate assessment of cystoid macular oedema (CMO) in patients with retinitis pigmentosa (RP) on spectral‐domain optical coherence tomography (SD‐OCT) is crucial for tracking disease progression and may serve as a therapeutic endpoint. Manual CMO segmentation is labour‐intensive and prone to variability, making artificial intelligence
Hind Almushattat, Jonathan Hensman, Yasmine el Allali, Coen de Vente, Clara I. Sánchez, Camiel J. F. Boon   +5 more
wiley   +1 more source

Comparison of vitrectomized with nonvitrectomized eyes after subtenon injection of triamcinolone acetonide to treat diabetic macular edema: Retrospective comparative Analysis of an interventional case series

Indian Journal of Ophthalmology, 2017
Purpose: Triamcinolone acetonide (TA) is an alternative option for diabetic macular edema thanks to its cost-benefit ratio and unique delivery route. We performed this study to compare vitrectomized with nonvitrectomized eyes treated with subtenon TA ...
Kang Yeun Pak, Beom Seok Choi, Sung Who Park, Ik Soo Byon, Ji Eun Lee   +4 more
doaj   +1 more source

Comparison of retinal function and macular structure after 27G pars plana vitrectomy with minimal heads‐up versus standard illumination in patients with idiopathic epiretinal membranes: A pilot randomized study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To analyse the clinical benefits of using the NGENUITY 3D Visualization System in vitreoretinal surgery with low levels of endoillumination, focusing on functional and structural retinal protection in patients with idiopathic epiretinal membranes (ERM). Design Prospective, randomized, comparative study.
Wojciech Lubiński, Tomasz Charabin, Karolina Podborączyńska‐Jodko, Maciej Mularczyk, Ewelina Lachowicz‐Gosławska   +4 more
wiley   +1 more source

Role of combined phacoemulsification and intravitreal injection of bevacizumab in prevention of postoperative macular edema in non-proliferative diabetic retinopathy

Journal of Current Ophthalmology, 2018
Purpose: To evaluate the role of combined phacoemulsification and intravitreal injection of bevacizumab in prevention of postoperative diabetic macular edema (DME) in patients with no diabetic retinopathy or non-proliferative diabetic retinopathy (NPDR ...
Alireza Khodabandeh, Shahed Fadaifard, Ali Abdollahi, Reza Karkhaneh, Ramak Roohipoor, Fatemeh Abdi, Hamed Ghasemi, Sam Habibollahi, Mehdi Mazloumi   +8 more
doaj  

Quantitative computerized color vision testing in diabetic retinopathy: A possible screening tool?

Oman Journal of Ophthalmology, 2013
Purpose: To evaluate the efficacy of a computerized color vision testing (Arden color contrast test) as a screening test for detection of diabetic macular edema (DME).
Rashid Al Saeidi, Marcus Kernt, Thomas C Kreutzer, Guenther Rudolph, Aljoscha S Neubauer, Christos Haritoglou   +5 more
doaj   +1 more source

Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]

, 2011
Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H., Koss, Michael Janusz, Pfister, Marcel   +2 more
core  

Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema.

Journal of Clinical Investigation, 2019
The majority of patients with diabetic macular edema (DME), the most common cause of vision loss in working-age Americans, do not respond adequately to current therapies targeting VEGFA.
Akrit Sodhi, T. Ma, D. Menon, M. Deshpande, Kathleen Jee, Aumreetam Dinabandhu, Jordan Vancel, Daoyuan Lu, S. Montaner   +8 more
semanticscholar   +1 more source

Diabetic Retinopathy and Diabetic Macular Edema [PDF]

, 2015
Diabetic retinopathy and diabetic macular edema result from chronic damage to the neurovascular structures of the retina. The pathophysiology of retinal damage remains uncertain but includes metabolic and neuroinflammatory insults. These mechanisms are addressed by intensive metabolic control of the systemic disease and by the use of ocular anti ...
Thomas W. Gardner, Steven R. Cohen
openaire   +3 more sources