Results 111 to 120 of about 46,348 (289)

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Livelayer: A Semi-Automatic Software Program for Segmentation of Layers and Diabetic Macular Edema in Optical Coherence Tomography Images [PDF]

arXiv, 2020
Given the capacity of Optical Coherence Tomography (OCT) imaging to display symptoms of a wide variety of eye diseases and neurological disorders, the need for OCT image segmentation and the corresponding data interpretation is latterly felt more than ever before.
arxiv  

Ropivacaine vs tetracaine in topical anesthesia for intravitreal injection [PDF]

, 2015
Aim: The object of the study was to evaluate the long term efficacy and safety of ropivacaine 0,5% vs tetracaine 0,5% for topical anesthesia in intravitreal injection of dexamethasone in patients with diabetic macular edema (DME) and anti-vascular ...
COLLINI, Saul, PACELLA, Elena, PACELLA, FERNANDA, SALDUCCI, Mauro, SMALDONE, GIANPAOLO, Troisi, Fabiana, TURCHETTI, PAOLO   +6 more
core   +1 more source

Drug Interaction With Advanced Therapies in Inflammatory Bowel Diseases: A Blind Spot to Tackle

United European Gastroenterology Journal, EarlyView.
Nathan Grellier, Julien Kirchgesner
wiley   +1 more source

Blockade of P2X7 receptors preserves blood retinal barrier integrity by modulating the plasmalemma vesicle‐associated protein: Implications for diabetic retinopathy

British Journal of Pharmacology, EarlyView.
Background and Purpose Plasmalemma vesicle‐associated protein (PLVAP) regulates transcytosis in vascular endothelial cells. PLVAP expression is increased in pathological conditions, such as diabetic retinopathy. P2X7 receptor antagonists have been shown to preserve blood‐retinal barrier (BRB) integrity.
Chiara Bianca Maria Platania, Francesca Lazzara, Kenneth Mitton, Naomi Haque, Wendelin Dailey, Federica Conti, Erika Giuffrida, Filippo Drago, Anca Hermenean, Cornel Balta, Hildegard Herman, Alina Ciceu, Maria Consiglia Trotta, Michele D'Amico, Giuseppe Nicosia, Settimio Rossi, Claudio Bucolo   +16 more
wiley   +1 more source

Correlation from undiluted vitreous cytokines of untreated central retinal vein occlusion with spectral domain optical coherence tomography [PDF]

, 2013
Purpose: To correlate inflammatory and proangiogenic key cytokines from undiluted vitreous of treatment-naïve central retinal vein occlusion (CRVO) patients with SD-OCT parameters. Methods: Thirty-five patients (age 71.1 years, 24 phakic, 30 nonischemic)
Cinatl, Jindrich, Koch, Frank H., Kohnen, Thomas, Koss, Michael Janusz, Pfister, Marcel, Rejdak, Robert, Ribeiro, Ramiro M., Rothweiler, Florian, Schubert, Ralf   +8 more
core   +1 more source

Safety and effectiveness of fingolimod in Japanese patients with multiple sclerosis: Results of a post‐marketing surveillance study

Clinical and Experimental Neuroimmunology, EarlyView.
Abstract Objective Fingolimod is the first oral sphingosine‐1‐phosphate receptor modulator approved in Japan for multiple sclerosis (MS). A large Japanese observational study of fingolimod in patients with MS was carried out to support its safety and effectiveness in a real‐world setting.
Noriko Sato, Koji Wakimoto, Kyoko Kato, Yutaka Susuta, Kengo Ueda, Yoshihisa Satou, Takayoshi Sasajima, Jun‐ichi Kira   +7 more
wiley   +1 more source

A RANDOMISED, COMPARATIVE STUDY OF GRID LASER AND SUBTHRESHOLD MICROPULSE DIODE LASER IN THE TREATMENT OF DIFFUSE DIABETIC MACULOPATHY [PDF]

, 2015
Objective: Diabetic retinopathy is a major cause of visual impairment in both developing and developed countries. The two important complicationsare macular edema and proliferative diabetic retinopathy.
., Rajarathnam, Chellakumar, Vikram, Vijai, Cornelius   +2 more
core   +1 more source

Management of Diabetic Macular Edema

Ophthalmic Research, 2017
Diabetic macular edema is a common condition frequently encountered by ophthalmologists. In this piece we briefly review its definition, pathogenesis, clinical aspects, imaging, and treatment.
Elad Moisseiev, Anat Loewenstein
openaire   +3 more sources

Factors associated with visual recovery after sub-Tenon injection of triamcinolone acetonide in diabetic macular edema

Clinical Ophthalmology, 2012
Hiroko Kawashima, Kenichi Mizukawa, Junichi KiryuDepartment of Ophthalmology, Kawasaki Medical School, Okayama, JapanBackground: The purpose of this retrospective chart review was to evaluate factors associated with improvement of visual acuity after a ...
Kawashima H, Mizukawa K, Kiryu J
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