Results 141 to 150 of about 83,999 (309)

The role of plasmalemma vesicle-associated protein in pathological breakdown of blood–brain and blood–retinal barriers: potential novel therapeutic target for cerebral edema and diabetic macular edema

open access: yesFluids and Barriers of the CNS, 2018
Breakdown of the blood–brain barrier (BBB) or inner blood–retinal barrier (BRB), induced by pathologically elevated levels of vascular endothelial growth factor (VEGF) or other mediators, can lead to vasogenic edema and significant clinical problems such
E. Bosma   +3 more
semanticscholar   +1 more source

Diagnostic Ability of Transverse Axial Images Obtained by Optical Coherence Tomography for Detecting Anterior Displacement of Peripapillary Tissues in Papilledema

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To evaluate the diagnostic ability of optical coherence tomography (OCT) images to detect posterior pole deformation and anterior displacement of the optic disc (ADOD) in papilledema before and after intracranial pressure reduction with medical treatment.
Gabriel Castilho S. Barbosa   +5 more
wiley   +1 more source

Subretinal pseudocysts: A novel OCT finding in diabetic macular edema

open access: yesAmerican Journal of Ophthalmology Case Reports, 2019
Purpose: to report the presence of a new structural optical coherence tomography (OCT) finding, namely subretinal pseudocysts, in a patient affected by diabetic retinopathy (DR).
Riccardo Sacconi   +5 more
doaj  

Aspectos atuais na fisiopatologia do edema macular diabético Recent aspects on physiopathology of diabetic macular edema

open access: yesRevista Brasileira de Oftalmologia, 2008
O edema macular é a principal causa de baixa visual em pacientes diabéticos. Seu mecanismo de formação é complexo e envolve alterações bioquímicas e estruturais.
Mário Martins dos Santos Motta   +2 more
doaj   +1 more source

Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat. [PDF]

open access: yes, 2019
Diabetic retinopathy is the most common microvascular complication of diabetes and is a major cause of blindness, but an understanding of the pathogenesis of the disease has been hampered by a lack of accurate animal models. Here, we explore the dynamics
Blodi, Barbara A   +10 more
core  

Update on corticosteroids for diabetic macular edema

open access: yesClinical Ophthalmology, 2016
Diabetic macular edema (DME) remains an important cause of visual loss. Although anti-vascular endothelial growth factor (VEGF) agents are generally used as first-line treatments for patients with center-involving DME, there is an important role for corticosteroids as well.
Harry W. Flynn   +3 more
openaire   +4 more sources

Cost‐effectiveness of fenofibrate versus standard care for reducing the progression of diabetic retinopathy: An economic evaluation based on data from the LENS trial

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims The LENS trial demonstrated that fenofibrate slowed the progression of diabetic retinopathy compared to placebo in participants with early diabetic eye disease. We assessed its cost‐effectiveness for reducing the progression of diabetic retinopathy versus standard care from a UK National Health Service perspective.
Graham Scotland   +166 more
wiley   +1 more source

Early Retinal and Choroidal Coat Thickness Changes after Intravitreal Dexamethasone Implant Injection for Diabetic Macular Edema

open access: yesBalkan Medical Journal, 2018
Background:Intravitreal steroid injection is one of the treatment options for diabetic macular edema. Dexamethasone implant is the most novel form of intravitreal steroid therapy.
Fatih Horozoğlu, Özkan Sever
doaj   +1 more source

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