Results 171 to 180 of about 46,348 (289)

Retinal Oxygen Kinetics and Hemodynamics in Choroidal Melanoma After Iodine‐125 Plaque Radiotherapy Using a Novel Structural‐Functional Imaging Analysis System

open access: yesCancer Medicine, Volume 14, Issue 8, April 2025.
Our study used advanced multimodal imaging techniques to demonstrate significant damage to retinal oxygen metabolism, vascular structure, and retinal blood flow in CM patients after iodine‐125 plaque radiotherapy. These findings may provide new pathophysiological insights into hypoxia in solid tumors after radiotherapy.
Haihan Zhang   +10 more
wiley   +1 more source

Global trends in diabetic eye disease research from 2012 to 2021

open access: yesNeural Regeneration Research
Diabetic eye disease refers to a group of eye complications that occur in diabetic patients and include diabetic retinopathy, diabetic macular edema, diabetic cataracts, and diabetic glaucoma.
Yuan Yuan   +6 more
doaj   +1 more source

Angiogenesis and targeted therapy in the tumour microenvironment: From basic to clinical practice

open access: yesClinical and Translational Medicine, Volume 15, Issue 4, April 2025.
Angiogenesis plays a key role in tumour progression, invasion and metastasis, so strategies targeting angiogenesis are gradually becoming an important direction in cancer therapy. Interactions between endothelial cells and stromal cells and immune cells in the tumour microenvironment are significant in angiogenesis.
Shuaixi Yang   +9 more
wiley   +1 more source

Association of metabolomic aging acceleration and body mass index phenotypes with mortality and obesity‐related morbidities

open access: yesAging Cell, Volume 24, Issue 4, April 2025.
Metabolomic aging acceleration may help stratify mortality and obesity‐related morbidities risk across different BMI categories. Weight management should address Individuals with overweight or obesity, regardless of metabolomic aging, while delaying metabolomic aging is crucial for all metabolomically older groups, including those with normal weight ...
Xiaomin Zeng   +9 more
wiley   +1 more source

Implementation of A New, Mobile Diabetic Retinopathy Screening Model Incorporating Artificial Intelligence in Remote Western Australia

open access: yesAustralian Journal of Rural Health, Volume 33, Issue 2, April 2025.
ABSTRACT Objective Diabetic retinopathy (DR) screening rates are poor in remote Western Australia where communities rely on outdated primary care‐based retinal cameras. Deep learning systems (DLS) may improve access to screening, however, require validation in real‐world settings.
Qiang Li   +5 more
wiley   +1 more source

Recognition of ophthalmology consultation and fundus examination among individuals with diabetes in Japan: A cross‐sectional study using claims‐questionnaire linked data

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 4, Page 1762-1772, April 2025.
Abstract Aims This study aimed to assess the relationship between individuals' recognition of ophthalmology consultation recommendations, their knowledge of the recommended frequency of diabetic retinopathy screening, and the likelihood of undergoing fundus examinations.
Kouko Yamamoto   +10 more
wiley   +1 more source

Real‐world evidence on the utilization, clinical and comparative effectiveness, and adverse effects of newer GLP‐1RA‐based weight‐loss therapies

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S2, Page 66-88, April 2025.
Abstract Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) have emerged as key agents for weight management, based on their marked efficacy as observed in randomized controlled trials. While still limited, real‐world studies on GLP‐1RA use in populations with obesity are increasingly available. This narrative review discusses contemporary real‐world
Reimar W. Thomsen   +3 more
wiley   +1 more source

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