Results 171 to 180 of about 83,999 (309)

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 7, Page 895-908, July 2025.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Oxidative Stress: Signaling Pathways, Biological Functions, and Disease

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu   +4 more
wiley   +1 more source

Relationship between Macular Thickness and the Ratio of Vascular Endothelial Growth Factor to Its Soluble Receptor 1 in Non-Proliferative Diabetic Retinopathy

open access: yesمجله دانشکده پزشکی اصفهان, 2012
Background: The goal of this study was to determine the ratio of vascular endothelial growth factor (VEGF) to soluble VEGF receptor 1 (SVEGFR1) in aqueous humor of patients with non-proliferative diabetic retinopathy (NPDR).
Zahra Hasanpour   +4 more
doaj  

AGREEMENT BETWEEN CLINICIAN AND READING CENTER GRADINGS OF DIABETIC RETINOPATHY SEVERITY LEVEL AT BASELINE IN A PHASE 2 STUDY OF INTRAVITREAL BEVACIZUMAB FOR DIABETIC MACULAR EDEMA [PDF]

open access: green, 2008
Ingrid U. Scott   +8 more
openalex   +1 more source

Commentary on “Prevalence, incidence, and risk factors of diabetic retinopathy and macular edema in patients with early and late‐onset type 2 diabetes mellitus”

open access: yes
Journal of Diabetes Investigation, EarlyView.
Fatemeh Rasulpur   +4 more
wiley   +1 more source

Detection of Diabetic Macular Edema: Nidek 3Dx Stereophotography Compared With Fundus Biomicroscopy

open access: hybrid, 1996
Antariksha Kiri   +4 more
openalex   +1 more source

CORRELATION BETWEEN MICROANEURYSMS AND RETINAL THICKNESS IN DIABETIC MACULAR EDEMA [PDF]

open access: green, 2008
Norman P. Blair   +3 more
openalex   +1 more source

Signs of Intracranial Hypertension in Chronic Inflammatory Polyradiculoneuropathies—A Cross Sectional Cohort Study

open access: yesEuropean Journal of Neurology, Volume 32, Issue 7, July 2025.
This prospective cross‐sectional study screened 27 patients with inflammatory polyradiculoneuropathy (IPN) for signs of intracranial hypertension (IH) using multimodal ophthalmological assessments (fundoscopy, perimetry, OCT, ultrasonography). Signs of IH were identified in 37% of patients.
Stefan Macher   +13 more
wiley   +1 more source

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