Results 31 to 40 of about 28,841 (163)

Diagnosing and monitoring diabetic macular edema: structural and functional tests. [PDF]

open access: yes, 2015
Diabetic macular edema remains a major cause of visual impairment in adults despite the use of intensive glycemic control, photocoagulation therapy and new intravitreal drugs in the treatment of this disease.
Midena, Edoardo, Vujosevic, Stela
core   +1 more source

Therapeutic potential of co-enzyme Q10 in retinal diseases [PDF]

open access: yes, 2017
Coenzyme Q10 (CoQ10) plays a critical role in mitochondrial oxidative phosphorylation by serving as an electron carrier in the respiratory electron transport chain.
Marcheggiani, Fabio   +6 more
core   +1 more source

Microperimetry and OCT angiography evaluation of patients with ischemic diabetic macular edema treated with monthly intravitreal bevacizumab: a pilot study

open access: yesInternational Journal of Retina and Vitreous, 2019
Background Functional and anatomical evaluation of patients with ischemic diabetic macular edema after monthly injections of Bevacizumab. Methods Five eyes from five patients with diabetic macular edema associated with macular ischemia in fluorescein ...
Felipe Pereira   +3 more
doaj   +1 more source

EFFECT OF ANTI-VEGF THERAPY ON THE STRUCTURAL STATE OF THE RETINA IN DIABETIC MACULAR EDEMA

open access: yesActa Biomedica Scientifica, 2016
Objective: to analyze the structural state of the central area of the retina in diabetic macular edema in the background anti-VEGF therapy. Methods. The study included 38 patients (40 eyes) with diabetic macular edema.
M. M. Bikbov   +2 more
doaj   +1 more source

Effect of Adding Oral Calcium Dobesilate to Laser Photocoagulation on the Macular Thickness in Patients with Diabetic Macular Edema: A Randomized Clinical Trial [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2014
Purpose: To evaluate the effect of oral calcium dobesilate (Doxium) on macular thickness in clinically significant macular edema (CSME). Methods: Overall, 71 eyes of 40 patients with non-proliferative diabetic retinopathy and clinically significant ...
Mostafa Feghhi   +3 more
doaj   +1 more source

Ultrastructure of neurovascular changes in human diabetic retinopathy [PDF]

open access: yes, 2018
The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation.
Artico, Marco   +9 more
core   +1 more source

Management of anterior chamber dislocation of a dexamethasone intravitreal implant: a case report [PDF]

open access: yes, 2016
Background Ozurdex is a 700 mcg dexamethasone intravitreal implant, approved for the management of macular edema secondary to retinal vein occlusion, and other related pathoglogiesAnterior chamber dislocation of Ozurdex represents an uncommon ...
AGOSTINELLI, Enzo   +6 more
core   +1 more source

Selective Laser Sintering 3D Printing of Drug‐Loaded Intravitreal Implants

open access: yesAdvanced Functional Materials, EarlyView.
Selective laser sintering enables the fabrication of biodegradable and biocompatible intravitreal implants with tunable microstructures for sustained drug delivery. By modulating laser scanning speed, the polymer matrix architecture is engineered to control the release kinetics of dexamethasone and riboflavin over several months. This approach offers a
Iria Seoane‐Viaño   +5 more
wiley   +1 more source

Comparison of Intravitreal Bevacizumab versus Triamcinolone for the Treatment of Diffuse Diabetic Macular Edema [PDF]

open access: yes, 2010
Background: Our purpose was to compare the effect of triamcinolone and bevacizumab (Avastin) on the retinal thickness and functional outcome in patients with diabetic macular edema. Methods and Materials: A collective of 32 patients, who had been treated
Al Saeidi, Rashid   +6 more
core   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

open access: yesAdvanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen   +12 more
wiley   +1 more source

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