Results 71 to 80 of about 28,841 (163)

SD‐OCT‐based biomarkers in predicting treatment outcomes of macular oedema secondary to retinal vein occlusion treated with anti‐VEGF therapy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the role of spectral domain optical coherence tomography (SD‐OCT)‐based biomarkers in predicting treatment response of macular oedema (MO) secondary to retinal vein occlusion (RVO) to anti‐vascular endothelial growth factor (VEGF) therapy.
Ken K. Tsang, Vivian W. K. Hui, Christopher M. K. Pang, Ziqi Tang, Dawei Yang, Truong X. Nguyen, Shaheeda Mohamed, Timothy Y. Y. Lai, Carol Y. Cheung, Simon K. H. Szeto   +9 more
wiley   +1 more source

Customizing AI‐based screening with real‐world data: Practical insights from diabetic retinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose Diabetic retinopathy (DR) is a leading cause of vision loss in middle‐aged adults globally. Although artificial intelligence (AI)‐based screening tools like IDx‐DR (classification) and Thirona RetCAD (regression) have shown high sensitivity in controlled settings, real‐world screening faces challenges due to missing or low‐quality ...
Broder Poschkamp, Liane Kantz, Petra Augstein, Allam Tayar, Lars Kaderali, Martin Busch, Beathe Bohl, Sebastian Paul, Lisa Lüdtke, Marie‐Christine Bründer, Daniel Schulz, Hanna Grabow, Elke Gens Dipl, Antonia Müller, Emily Martin, Wolfgang Kerner, Jörg Reindel, Andreas Stahl   +17 more
wiley   +1 more source

Effect of Adding Losartan to Bevacizumab for Treating Diabetic Macular Edema

Journal of Ophthalmology, 2020
Introduction. Diabetic retinopathy is the most common cause of visual loss and blindness in the age group of 20 to 64 years. This study aimed to evaluate the efficacy of oral Losartan adjuvant therapy in combination with intravitreal injection of ...
Fariba Ghassemi, Abdulrahim Amini, Masoud Yasemi, Amin Nabavi, Mohammadkarim Johari   +4 more
doaj   +1 more source

Micro-implant d'acétonide de fluocinolone (ILUVIEN(®)) pour l'oedème maculaire diabétique chronique [Fluocinolone acetonide (ILUVIEN®) micro-implant for chronic diabetic macular edema]. [PDF]

, 2015
Diabetic macular edema (DME) is a frequent complication of diabetic retinopathy and may cause severe visual loss. In this article, we examine the pathophysiology of DME and review various treatment options, such as laser photocoagulation, anti-vascular ...
Behar-Cohen, F., Soubrane, G.
core   +1 more source

Characterising PRPF31‐associated retinal dystrophy: Clinical insights from baseline data in a natural history study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To characterise the baseline clinical features and genotypes of adults with pre‐mRNA processing factor 31 (PRPF31)‐associated retinal dystrophy (RD) enrolled in a prospective, multicentre 4‐year natural history study, and to explore correlations between selected baseline parameters.
Kathrine Olaussen Eriksen, Jon Roger Eidet, Ulrika Kjellström, Jacopo Baldesi, Ragnheidur Bragadóttir, Leonardo Colombo, Josephine Prener Holtan   +6 more
wiley   +1 more source

Diabetic macular edema: it is more than just VEGF [version 1; referees: 2 approved]

F1000Research, 2016
Diabetic macular edema is a serious visual complication of diabetic retinopathy. This article reviews the history of previous and current therapies, including laser therapy, anti-vascular endothelial growth factor agents, and corticosteroids, that have ...
Michael A. Singer, Daniel S. Kermany, Jana Waters, Michael E. Jansen, Lyndon Tyler   +4 more
doaj   +1 more source

Topical Interferon Alpha 2b in the Treatment of Refractory Diabetic Macular Edema

Journal of Ophthalmic & Vision Research, 2020
Purpose: To report the efficacy of topical interferon alpha 2b in the treatment of refractory diabetic macular edema. Methods: In this retrospective interventional case series, five eyes of three individuals with diabetic macular edema resistant to
Arash Maleki, Andrew Phillips Stephenson, Fedra Hajizadeh   +2 more
doaj   +1 more source

Neovascular age‐related macular degeneration without drusen

Acta Ophthalmologica, EarlyView.
Abstract Purpose To describe the clinical characteristics and 1‐year follow‐up of patients with neovascular AMD (nAMD) without drusen in either eye. Methods This is a multicentre retrospective cohort study in three tertiary referral centres in The Netherlands. We included patients of 55 years or older with nAMD in one or both eyes, without the presence
Marc J. Sirks, Elon H. C. van Dijk, Husein Ghalayini, Somayeh Bazdar, WeiFeng Yu, Suzanne Yzer, José P. Martinez Ciriano, Reinier O. Schlingemann, Roselie M. H. Diederen, Camiel J. F. Boon   +9 more
wiley   +1 more source

Investigation of adaptive optics imaging biomarkers for detecting pathological changes of the cone mosaic in patients with type 1 diabetes mellitus [PDF]

, 2016
Purpose To investigate a set of adaptive optics (AO) imaging biomarkers for the assessment of changes of the cone mosaic spatial arrangement in patients with type 1 diabetes mellitus (DM1).
Giannini, Daniela, Lombardo, Giuseppe, Lombardo, Marco, Parravano, Mariacristina, Serrao, Sebastiano, Ziccardi, Lucia   +5 more
core   +4 more sources

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source