Results 81 to 90 of about 50,591 (247)

Expression profile of circular RNAs in type 2 diabetes mellitus patients with retinopathy

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetic retinopathy (DR) is a prevalent chronic complication of type 2 diabetes mellitus (T2DM), contributing significantly to vision impairment. Circular RNAs (circRNAs) have emerged as key regulators in the pathogenesis of DR.
Wencheng An, Bingyan Wang, Fang Chen, Bo An, Shujing Zhou, Lin Jiang, Zhijun Cui, Xiaohong Ou, Wei Huang, Huixian Yan   +9 more
wiley   +1 more source

Diabetic macular edema: it is more than just VEGF [version 1; referees: 2 approved]

F1000Research, 2016
Diabetic macular edema is a serious visual complication of diabetic retinopathy. This article reviews the history of previous and current therapies, including laser therapy, anti-vascular endothelial growth factor agents, and corticosteroids, that have ...
Michael A. Singer, Daniel S. Kermany, Jana Waters, Michael E. Jansen, Lyndon Tyler   +4 more
doaj   +1 more source

Effect of Adding Losartan to Bevacizumab for Treating Diabetic Macular Edema

Journal of Ophthalmology, 2020
Introduction. Diabetic retinopathy is the most common cause of visual loss and blindness in the age group of 20 to 64 years. This study aimed to evaluate the efficacy of oral Losartan adjuvant therapy in combination with intravitreal injection of ...
Fariba Ghassemi, Abdulrahim Amini, Masoud Yasemi, Amin Nabavi, Mohammadkarim Johari   +4 more
doaj   +1 more source

Cost-effectiveness of ranibizumab in treatment of diabetic macular oedema (DME) causing visual impairment : evidence from the RESTORE trial [PDF]

, 2012
Background/aims To evaluate the cost-effectiveness of ranibizumab as either monotherapy or combined with laser therapy, compared with laser monotherapy, in the treatment of diabetic macular oedema (DME) causing visual impairment from a UK healthcare ...
Annemans, Lieven, Gairy, Kerry, Gallagher, Meghan, Hasan, Rafiq, Knudsen, Martin, Mitchell, Paul, Onwordi, Henrietta, Thomas, Simu   +7 more
core   +3 more sources

REal-world treatment outcomes after delayed intRavitreal therapy in center-involving diabetic macular edema – RETORT study [PDF]

, 2023
Sai Prashanti Chitturi, Ramesh Venkatesh, Rubble Mangla, Yash Parmar, Rohini Sangoram, Naresh Kumar Yadav, Jay Chhablani   +6 more
openalex   +1 more source

Erythrocyte deformability correlates with microvascular ischemia and disease severity in diabetic retinopathy

Journal of Diabetes Investigation, EarlyView.
Under physiological conditions, deformable erythrocytes pass smoothly through the capillary network, maintaining retinal capillary perfusion (A). In pathological conditions, reduced erythrocyte deformability causes irregular passage and stagnation within capillaries, resulting in localized blood flow stasis and microvascular congestion, leading to ...
Ye Eun Han, Joon Seo Lim, Yulim Kim, Inhye Kim, Jun Sung Moon, Junyeop Lee   +5 more
wiley   +1 more source

A Smartphone-Based Tool for Rapid, Portable, and Automated Wide-Field Retinal Imaging. [PDF]

, 2018
Purpose:High-quality, wide-field retinal imaging is a valuable method for screening preventable, vision-threatening diseases of the retina. Smartphone-based retinal cameras hold promise for increasing access to retinal imaging, but variable image quality
Davila, Jose R, Echanique, Chris, Fletcher, Daniel A, Keenan, Jeremy, Kim, Tyson N, Li, Patrick, Loumou, Panagiota, Loury, PJ, Maamari, Robi N, Margolis, Todd, Myers, Frank, Paulus, Yannis M, Reber, Clay, Switz, Neil A, Webster, Doug, Woodward, Maria A   +15 more
core  

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

Experimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng, Susan Patricia Mollan   +1 more
wiley   +1 more source

Topical Interferon Alpha 2b in the Treatment of Refractory Diabetic Macular Edema

Journal of Ophthalmic & Vision Research, 2020
Purpose: To report the efficacy of topical interferon alpha 2b in the treatment of refractory diabetic macular edema. Methods: In this retrospective interventional case series, five eyes of three individuals with diabetic macular edema resistant to
Arash Maleki, Andrew Phillips Stephenson, Fedra Hajizadeh   +2 more
doaj   +1 more source