Results 261 to 270 of about 182,106 (353)

Association of the IL‐6R rs2228145 polymorphism with diabetic nephropathy: A case‐control study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction The pathogenesis of diabetes mellitus (DM) and its complications has been previously linked to elevated levels of interleukin‐6 (IL‐6); IL‐6 triggers intracellular pathways through interaction with the IL‐6 receptor (IL‐6R). This study aimed to determine the association of single nucleotide polymorphisms (SNPs) IL‐6 −597G/A ...
Pavla Izakovicova, Simona Slezakova, Tereza Deissova, Hana Poskerova, Petra Borilova Linhartova, Ladislav Dusek, Katerina Kankova, Lydie Izakovicova Holla   +7 more
wiley   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization. [PDF]

Adv Sci (Weinh)
Xuan C, Chen D, Zhang S, Li C, Fang Q, Chen D, Liu J, Jiang X, Zhang Y, Shen W, Cai G, Chen X, Li P.   +12 more
europepmc   +1 more source

Elevated amputation rates in COVID‐19 survivors: Insights from a large‐scale Japanese cohort study

Journal of Diabetes Investigation, EarlyView.
COVID‐19 is associated with a long‐term increased risk of amputation, persisting for more than 2 years post infection. These findings highlight the need for vigilant vascular monitoring and early intervention to mitigate the long‐term complications of COVID‐19.
Daisuke Miyamori, Shuhei Yoshida, Masanori Ito   +2 more
wiley   +1 more source

Uhrf1 downregulation promotes β‐cell dedifferentiation by decreasing Foxo1 expression in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
This finding reveals the important role of Uhrf1 in the β‐cell dedifferentiation of T2D, providing a potential target for its treatment. ABSTRACT Background Islet β‐cell dedifferentiation is a major pathological mechanism of type 2 diabetes (T2D). Forkhead box o1 (Foxo1) is a master regulator of β‐cell dedifferentiation.
Lanfang Fu, Juyun Zhang, Zhu Lin, Xubiao Meng   +3 more
wiley   +1 more source

Identification of Shared Biomarkers in Chronic Kidney Disease and Diabetic Nephropathy Using Single-Cell Sequencing. [PDF]

Diabetes Metab Syndr Obes
Ma JS, Yang J, Wang WC, Quan YX, Liao XN, Bai YH, Jiang HY.   +6 more
europepmc   +1 more source

Clinical use and monitoring of adverse effects of sodium‐glucose cotransporter‐2 inhibitors in persons with type 1 diabetes mellitus

Journal of Diabetes Investigation, EarlyView.
Multiple regression analysis revealed that diuretic use was an independent risk factor for discontinuation of SGLT2i. ABSTRACT Aims This study aimed to evaluate the factors contributing to insulin dosage adjustment and the risk of sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) discontinuation in persons with type 1 diabetes mellitus (T1DM) starting ...
Chinatsu Sakai, Shinichi Tamaru, Keiji Sugai, Hironori Takeuchi, Ryo Suzuki   +4 more
wiley   +1 more source

Research progress on small extracellular vesicles in diabetic nephropathy. [PDF]

Front Cell Dev Biol
Yu B, Wang L, Mao Y, Hu X, Lu Y, He J, Yuan X, Zhang M, Chen Z.   +8 more
europepmc   +1 more source

The cholesterol‐HDL‐glucose (CHG) index and traditional adiposity markers in predicting diabetic retinopathy and nephropathy

Journal of Diabetes Investigation, EarlyView.
This study explores the association of visceral adiposity index (VAI) and lipid accumulation product (LAP), markers of visceral adiposity, with diabetic nephropathy and retinopathy. The findings revealed that VAI and LAP values were significantly elevated in diabetic nephropathy but showed no significant association with diabetic retinopathy.
Merve Çatak, Şerife Gülhan Konuk, Sema Hepsen   +2 more
wiley   +1 more source

Editorial: Diagnosis, prevention and treatment in diabetic nephropathy, volume III. [PDF]

Front Endocrinol (Lausanne)
Rando MM, Biscetti F, Flex A.
europepmc   +1 more source

Phenotypic characteristics of diabetic neuropathic pain and factors associated in patients with Diabetes Mellitus‐type 2

Journal of Diabetes Investigation, EarlyView.
Four phenotypic groups of patients with diabetic neuropathic pain were found. Intensity, duration of pain, and the level of anxiety were the factors associated with belonging to the groups with worse characteristics. ABSTRACT Aims/Introduction To identify subgroups of patients with diabetic neuropathic pain according to their phenotypic characteristics
Helena De Sola, María Dueñas, Inmaculada Failde, Jenifer Palomo‐Osuna, Cristina Naranjo, Alejandro Salazar   +5 more
wiley   +1 more source