Results 231 to 240 of about 91,203 (305)

Association of long noncoding RNA MEG3 genetic variants with the risk of diabetic neuropathy. [PDF]

Int J Med Sci
Fan YC, Yang PJ, Liu YF, Chang LC, Su SC, Yang SF.   +5 more
europepmc   +1 more source

Electrophysiological diagnosis using the coefficient of variation of R‐R intervals and a point‐of‐care nerve conduction device is highly correlated to the diagnosis of diabetic polyneuropathy using conventional electromyographs

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction While treatment for diabetic polyneuropathy (DPN) is still developing, progress has stagnated. The alignment between pathological neurodegeneration in DPN and patients' subjective symptoms is often low, yet these symptoms are frequently used for diagnosis.
Tatsuhito Himeno, Hideki Kamiya, Yuka Shibata, Masato Kase, Hiromi Nakai‐Shimoda, Dai Yamagami, Masahiro Saito, Teruo Jojima, Aiko Arimura, Kenta Murotani, Chieko Suzuki, Hiroki Mizukami, Takahisa Deguchi, Yoshimasa Aso, Jiro Nakamura   +14 more
wiley   +1 more source

Curcumin as a promising therapeutic agent for diabetic neuropathy: from molecular mechanisms to functional recovery. [PDF]

Diabetol Metab Syndr
Barati S, Yadegari A, Shahmohammadi M, Azami F, Tahmasebi F, Rouhani MR, Kazemi S, Asl ER.   +7 more
europepmc   +1 more source

Evaluation of the effectiveness and safety of ONO‐2910 for the treatment of diabetic polyneuropathy: An early Phase IIa, multicenter, randomized, placebo‐controlled, double‐blind study in Japanese patients

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Diabetic polyneuropathy (DPN) is common in patients with diabetes. Its symptoms include pain, numbness, and impaired neurosensory function. ONO‐2910 promotes Schwann cell differentiation and is being developed for DPN. Materials and Methods This Phase IIa randomized controlled trial evaluated the effectiveness and safety of ...
Yukiko Onishi, Takeshi Osonoi, Norio Takahashi, Toru Takiguchi, Eiichiro Morishima, Yoshimasa Aso, Kenji Sekiguchi, Hideki Kamiya, Jiro Nakamura   +8 more
wiley   +1 more source

Artificial Intelligence Algorithm to Screen for Diabetic Neuropathy: A Pilot Study. [PDF]

Biomedicines
Sartore G, Ragazzi E, Pegoraro F, Pagno MG, Lapolla A, Piarulli F.   +5 more
europepmc   +1 more source

Impact of glycemic variability on early detection of sudomotor dysfunction: Implications for early intervention and personalized treatment

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background This study investigates the impact of glycemic variability on sudomotor dysfunction in type 2 diabetes mellitus. Methods A total of 206 type 2 diabetes mellitus patients and 34 healthy controls were included. Sweat function (SF) was assessed using electrochemical conductance of hands (HESC) and feet (FESC).
Yang Ou, Xiao‐feng Hu, Zhi Liang, Xiao‐hui Zhang, Yi‐kun Zhou   +4 more
wiley   +1 more source

Beyond pain relief: the effects of chronic opioid use on brain structure and function in diabetic neuropathy-a multimodal neuroimaging study. [PDF]

Diabetologia
Sloan G, Teh K, Greig M, Shillo P, Caunt S, Wilkinson ID, Tesfaye S, Selvarajah D.   +7 more
europepmc   +1 more source

Diabetic peripheral neuropathy as measured using a point‐of‐care sural nerve conduction device is associated with a faster decline in renal function in patients with type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
Point‐of‐care assessment of diabetic peripheral neuropathy with DPN‐Check® was independently associated with a faster decline in renal function in type 2 diabetes, highlighting its potential as a tool to identify patients at high risk of kidney disease progression. ABSTRACT Aims/Introduction Diabetic peripheral neuropathy (DPN) is a common complication
Tatsuya Fukuda, Akiko Fujii, Taro Akihisa, Naoya Otsubo, Tetsuya Yamada, Chisato Maki   +5 more
wiley   +1 more source

Causal Relationships Between Neuropathic Pain and Alzheimer's Disease: A Multi-Omics Mendelian Randomization Study with Exploratory Evidence of a Potential Protective Role of Diabetic Neuropathy. [PDF]

J Pain Res
Li X, Zhang C, Liu D, Shang H, Wang K, Lin X, Zheng J.   +6 more
europepmc   +1 more source

Risk factors for persistent decline in eGFR of Japanese patients with diabetes: Analysis using a large‐scale diabetes registry J‐DREAMS

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction This study aimed to identify clinical predictors associated with sustained decline in estimated glomerular filtration rate (eGFR) among Japanese individuals diagnosed with diabetes mellitus. Materials and Methods We conducted a retrospective analysis using J‐DREAMS (Japan Diabetes compREhensive database project based on an ...
Kota Yamada, Mitsuru Ohsugi, Yuichiro Ito, Hiroki Uchida, Takumi Lee, Kohjiro Ueki   +5 more
wiley   +1 more source