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Continuum, 2023
This article provides an up-to-date review of the diagnosis and management of the most common neuropathies that occur in patients with diabetes.The prevalence of diabetes continues to grow worldwide and, as a result, the burden of diabetic neuropathies is also increasing. Most diabetic neuropathies are caused by hyperglycemic effects on small and large
Melissa A, Elafros, Brian C, Callaghan
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This article provides an up-to-date review of the diagnosis and management of the most common neuropathies that occur in patients with diabetes.The prevalence of diabetes continues to grow worldwide and, as a result, the burden of diabetic neuropathies is also increasing. Most diabetic neuropathies are caused by hyperglycemic effects on small and large
Melissa A, Elafros, Brian C, Callaghan
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Diabetes Care, 1992
Diabetic neuropathy is a common complication of diabetes that may be associated both with considerable morbidity (painful polyneuropathy, neuropathic ulceration) and mortality (autonomic neuropathy). The epidemiology and natural history of diabetic neuropathy is clouded with uncertainty, largely caused by confusion in the definition and measurement of ...
A I, Vinik +5 more
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Diabetic neuropathy is a common complication of diabetes that may be associated both with considerable morbidity (painful polyneuropathy, neuropathic ulceration) and mortality (autonomic neuropathy). The epidemiology and natural history of diabetic neuropathy is clouded with uncertainty, largely caused by confusion in the definition and measurement of ...
A I, Vinik +5 more
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Annual Review of Medicine, 1990
Diabetic neuropathy, the most common peripheral neuropathy in the Western world, is responsible for most limb amputations and considerable morbidity in diabetic patients. Although it is a sequela to insulin deficiency and/or hyperglycemia, its exact pathogenetic mechanism remains unclear.
D A, Greene +3 more
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Diabetic neuropathy, the most common peripheral neuropathy in the Western world, is responsible for most limb amputations and considerable morbidity in diabetic patients. Although it is a sequela to insulin deficiency and/or hyperglycemia, its exact pathogenetic mechanism remains unclear.
D A, Greene +3 more
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Muscle & Nerve, 2020
AbstractDiabetic neuropathies are the most common type of neuropathies seen in clinical practice. These neuropathies can range clinically from asymptomatic to manifesting symptoms caused by motor, sensory, and autonomic nerve dysfunction. These neuropathies can affect the peripheral nervous system, pain receptors, cardiovascular, urogenital, and ...
Kamakshi, Patel +2 more
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AbstractDiabetic neuropathies are the most common type of neuropathies seen in clinical practice. These neuropathies can range clinically from asymptomatic to manifesting symptoms caused by motor, sensory, and autonomic nerve dysfunction. These neuropathies can affect the peripheral nervous system, pain receptors, cardiovascular, urogenital, and ...
Kamakshi, Patel +2 more
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Annals of Neurology, 1984
AbstractPeripheral nerve disorders are important late complications of diabetes mellitus. Polyneuropathy, which may involve varying proportions of sensory, motor, and autonomic fibers, is considered the consequence of metabolic derangements that result from chronic hyperglycemia.
M J, Brown, A K, Asbury
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AbstractPeripheral nerve disorders are important late complications of diabetes mellitus. Polyneuropathy, which may involve varying proportions of sensory, motor, and autonomic fibers, is considered the consequence of metabolic derangements that result from chronic hyperglycemia.
M J, Brown, A K, Asbury
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Clinics in Endocrinology and Metabolism, 1972
Many factors contribute to the nerve damage of diabetes--metabolic (myo-inositol), microvascular, glycosylation and ageing. The variety of clinical syndromes indicates the complexity of the disease. Measurement of peripheral and autonomic nerve function is improving allowing the establishment of prospective natural history and therapeutic studies ...
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Many factors contribute to the nerve damage of diabetes--metabolic (myo-inositol), microvascular, glycosylation and ageing. The variety of clinical syndromes indicates the complexity of the disease. Measurement of peripheral and autonomic nerve function is improving allowing the establishment of prospective natural history and therapeutic studies ...
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Current Opinion in Neurology, 1994
It has been generally accepted that diabetic neuropathy is associated with substantial morbidity and increased mortality, and that aldose reductase inhibitors are of potential therapeutic value, whereas the beneficial effect of strict insulin treatment is questionable.
Jakobsen, J, Sidenius, P
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It has been generally accepted that diabetic neuropathy is associated with substantial morbidity and increased mortality, and that aldose reductase inhibitors are of potential therapeutic value, whereas the beneficial effect of strict insulin treatment is questionable.
Jakobsen, J, Sidenius, P
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Endocrinology and Metabolism Clinics of North America, 2013
Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus, leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care. The clinical assessment of diabetic peripheral neuropathy and its treatment options are multifactorial.
Aaron I, Vinik +3 more
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Diabetic neuropathy (DN) is the most common and troublesome complication of diabetes mellitus, leading to the greatest morbidity and mortality and resulting in a huge economic burden for diabetes care. The clinical assessment of diabetic peripheral neuropathy and its treatment options are multifactorial.
Aaron I, Vinik +3 more
openaire +4 more sources
Physical Medicine and Rehabilitation Clinics of North America, 2001
Diabetes mellitus is a systemic disorder with a significant impact on the peripheral nervous system. Over half of the 15 million patients with diabetes mellitus in the United States have some form of diabetic neuropathy. Individuals with diabetes may develop acute or subacute painful polyneuropathy, proximal motor neuropathy, autonomic neuropathy ...
T H, Wein, J W, Albers
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Diabetes mellitus is a systemic disorder with a significant impact on the peripheral nervous system. Over half of the 15 million patients with diabetes mellitus in the United States have some form of diabetic neuropathy. Individuals with diabetes may develop acute or subacute painful polyneuropathy, proximal motor neuropathy, autonomic neuropathy ...
T H, Wein, J W, Albers
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Seminars in Neurology, 2005
Diabetic neuropathy is not a single entity but manifests as several different clinical syndromes. It is likely that different pathophysiological mechanisms contribute to the development of the neuropathy, including metabolic alterations, microvascular changes, and inflammatory changes.
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Diabetic neuropathy is not a single entity but manifests as several different clinical syndromes. It is likely that different pathophysiological mechanisms contribute to the development of the neuropathy, including metabolic alterations, microvascular changes, and inflammatory changes.
openaire +2 more sources