Results 121 to 130 of about 316,189 (194)

In Vivo Ultrasound Characterization of the Tibial Nerve at the Supramalleolar Region

Journal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Background Accurate knowledge of the supramalleolar anatomy of the tibial nerve is essential for safe ultrasound‐guided procedures and proximal nerve interventions in the foot and ankle. However, quantitative in vivo ultrasound reference data describing its positional anatomy at this level remain scarce.
María Benimeli‐Fenollar, Cecili Macián‐Romero, Lucía Carbonell‐José, María José Chiva‐Miralles, Enrique Sanchis‐Sales, Adrián Jordá‐Vallés, Vicent Tomás‐Martínez   +6 more
wiley   +1 more source

The Effect of Micronutrient Intake and Supplementation on Prevalent Diabetes‐Related Foot Ulcer and Incident Hospitalisation for Diabetes‐Related Foot Ulcer in Type 2 Diabetes: The Fremantle Diabetes Study Phase 2

Journal of Foot and Ankle Research, Volume 19, Issue 3, September 2026.
ABSTRACT Objective To determine whether micronutrient intake and/or supplementation is associated with prevalent diabetes‐related foot ulcer (DFU) and/or incident hospitalisation for DFU in type 2 diabetes. Research Design and Methods Participants with type 2 diabetes from the community‐based Fremantle Diabetes Study Phase II (FDS2; 1499 participants ...
Emma J. Hamilton, Wendy A. Davis, Ranita Siru, Mendel Baba, Timothy M. E. Davis   +4 more
wiley   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, Volume 2, Issue 3, Page 484-497, September 2026.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Evaluation of Topiramate Efficacy on Neuropathic Pain in Patients With Diabetic Polyneuropathy

Acta Medica Iranica, 2019
Polyneuropathy is one of the most common and disabling complications of diabetes. Severe pain is one of the complications of diabetic polyneuropathy .Over the years, many drugs for the treatment of the pain in diabetic neuropathy have been tried. However,
Sedigheh Shamsinejad, Ali Davati, Mehrdad Roughani, Amir Ghasemlouie, Siamak Afshinmajd   +4 more
doaj  

Deciphering the Mechanisms of Statin–Ezetimibe Drug Combinations Using Boolean Logical Modeling and Transcriptomic Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACT Drug Combinations offer increased therapeutic efficacy and reduced toxicity compared with single agents. Understanding a drug combination's mechanisms of action (MoA) can provide important insights into therapeutic efficacy. The MoA of many FDA‐approved drugs, however, often remains unclear.
Rui‐Sheng Wang, Matteo Pedrelli, Osman Ahmed, Garagnani Paolo, Paolo Parini, Joseph Loscalzo   +5 more
wiley   +1 more source

Pathogenetic treatment of diabetic polyneuropathy

, 2017
The authors have studied the effect of mildronat and thiotriazolin on the processes of lipid peroxidation, the oxidative modification of proteins and the state of the blood antioxidant system 3 and 6 months following a course of multimodality treatment ...
Pavlovych, L.B., Bilous, I.I.
core   +2 more sources

Liquid crystal thermography in neuropathic assessment of the diabetic foot. [PDF]

Primary aetiologic factors of diabetic foot disease include peripheral neuropathy and peripheral vascular disease. Assessment of circulation, neuropathy, and foot pressure is employed routinely to determine the risk of foot ulceration in the patient ...
Bharara, Manish
core   +3 more sources

Glucagon‐Like Peptide‐1 Receptor Agonists and Incident Major Adverse Liver Outcomes in People With Type 2 Diabetes and Metabolic Dysfunction‐Associated Steatotic Liver Disease

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8277-8287, September 2026.
ABSTRACT Aims Treatment options for metabolic dysfunction‐associated steatotic liver disease (MASLD) are limited. While glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) and sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors improve cardiovascular outcomes, comparative effectiveness on liver‐related outcomes remains unclear.
Gregor A. Maier, Ramon A. Hofmann, Michael Roden, Wolfgang Rathmann, Oliver Kuss   +4 more
wiley   +1 more source

Asymptomatic Carrier Neurologic Assessment: A Tool for Early Detection of Symptomatic Transition in Pathogenic TTR Gene Variant Carriers

European Journal of Neurology, Volume 33, Issue 9, September 2026.
There are no tools to support early detection of ATTRv signs/symptoms or to identify risk of transition to clinically detectable disease in carriers of pathogenic ATTRv variants. This retrospective cohort study describes the ACNA, a brief 23‐item assessment for use in routine clinical visits.
Isabel Conceição, Juan González‐Moreno, Andoni Echaniz‐Laguna, Kuangnan Xiong, Adam Castaño, Jonathan C. Fox, Julian D. Gillmore, Pablo Garcia‐Pavia, Mary M. Reilly   +8 more
wiley   +1 more source

Long‐Term Safety and Efficacy of Efgartigimod PH20 in Chronic Inflammatory Demyelinating Polyradiculoneuropathy: ADHERE/ADHERE+ Trial Interim Analysis

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background and Aims In ADHERE, subcutaneous efgartigimod PH20 (1000 mg once weekly) was effective and well tolerated in participants with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). ADHERE+ is an open‐label extension of ADHERE assessing long‐term safety and efficacy. Methods Eligible participants from ADHERE run‐in period
Jeffrey A. Allen, Geoffrey Istas, Satoshi Kuwabara, Trevor Mole, Luis Querol, Simon Rinaldi, Mark Stettner, Benjamin Van Hoorick, Richard A. Lewis   +8 more
wiley   +1 more source