Results 21 to 30 of about 615,781 (294)

Analysis of Macrophages and Peptidergic Fibers in the Skin of Patients With Painful Diabetic Polyneuropathy

Neurology: Neuroimmunology & Neuroinflammation, 2021
Background and Objectives The mechanisms of pain in patients with diabetic polyneuropathy are unknown. Studies have suggested a role of inflammation and increased neuropeptides peripherally in pain generation.
S. S. Gylfadottir, M. Itani, A. G. Kristensen, H. Tankisi, T. S. Jensen, S. Sindrup, D. Bennett, J. Nyengaard, N. Finnerup, P. Karlsson   +9 more
semanticscholar   +1 more source

Selective blood-nerve barrier leakiness with claudin-1 and vessel-associated macrophage loss in diabetic polyneuropathy

Journal of molecular medicine, 2021
Diabetic polyneuropathy (DPN) is the most common complication in diabetes and can be painful in up to 26% of all diabetic patients. Peripheral nerves are shielded by the blood-nerve barrier (BNB) consisting of the perineurium and endoneurial vessels.
Adel Ben-Kraiem, Reine-Solange Sauer, Carla Norwig, M. Popp, Anna-Lena Bettenhausen, Mariam Sobhy Atalla, A. Brack, R. Blum, K. Doppler, H. Rittner   +9 more
semanticscholar   +1 more source

Association of glycemic variability assessed by continuous glucose monitoring with subclinical diabetic polyneuropathy in type 2 diabetes patients

Journal of Diabetes Investigation, 2021
Diabetic peripheral neuropathy is a common diabetes‐related microvascular complication. The relationship between peripheral nerve function and glucose variability is unclear.
Jiemin Pan, Xinfeng Yan, Fengwen Li, Yinan Zhang, Lan Jiang, Congrong Wang   +5 more
semanticscholar   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Clinical use of an analysis of oxidative stress and IL-6 as the promoters of diabetic polyneuropathy.

Medicinski glasnik, 2021
Aim To investigate interleukin 6 (IL-6) values depending on duration of diabetes mellitus (DM) and evaluate possible correlation with diabetic polyneuropathy.
Emina Karahmet, B. Prnjavorac, T. Bego, A. Softič, L. Begić, E. Begić, Esma Karahmet, L. Prnjavorac, I. Prnjavorac   +8 more
semanticscholar   +1 more source

Falls and fractures associated with type 2 diabetic polyneuropathy: A cross‐sectional nationwide questionnaire study

Journal of Diabetes Investigation, 2021
To examine the prevalence of falls and fractures, and the association with symptoms of diabetic polyneuropathy (DPN) in patients with recently diagnosed type 2 diabetes.
K. Khan, D. Christensen, S. K. Nicolaisen, S. S. Gylfadottir, T. Jensen, J. Nielsen, R. Thomsen, H. Andersen   +7 more
semanticscholar   +1 more source

Alterations of retinal thickness measured by optical coherence tomography correlate with neurophysiological measures in diabetic polyneuropathy

Journal of Diabetes Investigation, 2021
Aims/Introduction Diabetic polyneuropathy (DPN) and diabetic retinopathy (DR) are traditionally regarded as microvascular complications. However, these complications may share similar neurodegenerative pathologies.
Yuichiro Yamada, Tatsuhito Himeno, Kotaro Tsuboi, Yuka Shibata, Miyuka Kawai, Yuriko Asada‐Yamada, Yusuke Hayashi, Emi Asano‐Hayami, Tomohide Hayami, Yuichiro Ishida, Yohei Ejima, Mikio Motegi, Saeko Asano, Makoto Kato, Eriko Nagao, Hiromi Nakai‐Shimoda, Takahiro Ishikawa, Yoshiaki Morishita, Masaki Kondo, Shin Tsunekawa, Yoshiro Kato, Takayuki Nakayama, Motohiro Kamei, Jiro Nakamura, Hideki Kamiya   +24 more
doaj   +1 more source

Risk factors for depression and anxiety in painful and painless diabetic polyneuropathy: A multicentre observational cross‐sectional study

European Journal of Pain, 2021
Despite the high prevalence of depression and anxiety in chronic pain conditions, current knowledge concerning emotional distress among painful diabetic polyneuropathy (pDSPN) and other diabetes mellitus (DM) sufferers is limited.
David Kec, A. Rajdova, J. Raputová, B. Adamová, I. Srotova, Eva Králíčková Nekvapilová, R. Michalčáková, Magda Horáková, J. Bělobrádková, J. Olšovský, P. Weber, G. Hajaš, M. Kaiserová, R. Mazanec, Veronika Potocková, E. Ehler, M. Forgác, F. Birklein, N. Üçeyler, C. Sommer, J. Bednařík, E. Vlčková   +21 more
semanticscholar   +1 more source

Sudomotor Testing of Diabetes Polyneuropathy [PDF]

Frontiers in Neurology, 2018
Objective: The performance of the Sudoscan technology for diagnosing diabetic polyneuropathy (DPN) was evaluated against the quantitative sudomotor axon reflex test (QSART). Furthermore, the association of Sudoscan with two clinical neuropathy scoring systems was evaluated. Methods: Forty-seven patients with type 2 diabetes (20 without DPN, 27 with DPN)
Elena Henkel, Manja Reimann, Markolf Hanefeld, Sarah-Maria Krieger, Rocco Haase, Tjalf Ziemssen   +5 more
openaire   +4 more sources

Sodium valproate in painful diabetic polyneuropathy

Acta Neurologica Scandinavica, 2003
Søren H. Sindrup, Michael W. Otto, Flemming W. Bach, Troels S. Jensen   +3 more
openalex   +5 more sources