Results 81 to 90 of about 14,476 (183)

Effects of Aging on Pain Tolerance: A Comparative Study of Heat Pain Thresholds and Tonic Heat and Cold Stimuli

European Journal of Pain, Volume 30, Issue 1, January 2026.
ABSTRACT Introduction Aging is known to impact both pain perception and modulation. While sensory thresholds have been extensively studied, age‐related changes in pain tolerance remain less conclusive. Additionally, limited research has explored whether thermal modality differentially affects pain tolerance in older adults.
Julia Devanne, Louise Trocmet
wiley   +1 more source

Altered Semmes–Weinstein monofilament test results are associated with oxidative stress markers in type 2 diabetic subjects

Journal of Translational Medicine, 2017
Background Different lines of evidence suggest that oxidative stress (OS) is implicated in the pathogenesis of diabetic neuropathy. The Semmes–Weinstein monofilament (SWM) test is an efficient tool for evaluating diabetic polyneuropathy and diabetic foot.
Sergio Martinez-Hervás, Mercedes Molina Mendez, José Folgado, Carmen Tormos, Pilar Ascaso, Marta Peiró, Jose T. Real, Juan F. Ascaso   +7 more
doaj   +1 more source

Reduced Descending Itch Inhibition in Peripheral Neuropathy Patients With Chronic Pruritus

European Journal of Pain, Volume 30, Issue 1, January 2026.
ABSTRACT Background Peripheral neuropathies (PNP) cause a wide range of symptoms of which pruritus and pain are a major burden to patients. Clarifying their mechanisms will facilitate the adequate symptom management. In contrast to neuropathic pain, neuropathic pruritus has long been understudied.
Jonas Eck, Stephan Bigalke, Martin Schmelz, Daniela Constanze Rosenberger, Bruno Pradier, Frank Rutsch, Claudia Sommer, Frank Birklein, Daniel Segelcke, Esther Pogatzki‐Zahn   +9 more
wiley   +1 more source

Langerhans cell activation in diabetic small fiber polyneuropathy [PDF]

, 2014
Ezequiel Piccione, JaNean K. Engelstad, Carilyn N. Wieland, Christopher J. Klein   +3 more
openalex   +1 more source

Response to High‐Dose Topical Capsaicin in Neuropathic Pain: Absence of Deep Pain as a Predictor of Analgesic Effect

European Journal of Pain, Volume 30, Issue 1, January 2026.
ABSTRACT Background Topical high‐dose capsaicin treatment is a recommended therapy for localised neuropathic pain with good tolerability and no identified drug interactions. However, it is not effective for every patient. So far, few parameters in patient history have been identified as predictors for response to capsaicin treatment.
Manon Sendel, Lena Ehmke, Andreas Dunst, Jan Vollert, Henrike Bruckmüller, Sandra Brügge, Stefanie Rehm, Janne Gierthmühlen, Dilara Kersebaum, Ingolf Cascorbi, Ralf Baron, Julia Forstenpointner   +11 more
wiley   +1 more source

Application of Pender's Health Promotion Model for Healthy Dietary Practice Promotion Among Type 2 Diabetes Mellitus Patients: A Quasi‐Experimental Study in Lalitpur District, Nepal

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Type 2 Diabetes Mellitus (T2DM) is a serious public health issue that is considered the leading cause of death. However, it can be controlled and treated with simple interventions, including good dietary practices. This study aims to assess the effect of a diabetes management self‐care program on dietary practices among ...
Anish Sharma Upreti, Bhagwan Aryal, Jyoti Kuikel, Mohan Kumar Sharma, Laxman Sigdel   +4 more
wiley   +1 more source

Lipoic Acid Ameliorates Lipopolysaccharide‐Induced Inflammation via Inhibition of Glycolysis in RAW264.7 Macrophages

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
Anti‐inflammatory mechanism of Lipoic acid. LA and siRNA‐HIF1α inhibited the expression of HIF1α and inflammatory factors such as IL‐6, IL‐18, TNF‐α, and IL‐1β in LPS‐induced macrophages. The researchers showed in this work that the anti‐inflammation was achieved through HIF1α/glycolysis axis.
Liduo Yue, Kai Wang, Rongyuan Wang, Linbei Lu, Lihong Fan   +4 more
wiley   +1 more source

Sural/Radial Amplitude Ratio: A Useful Tool to Diagnose Non‐Length‐Dependent Neuropathy

Muscle &Nerve, Volume 73, Issue 1, Page 34-40, January 2026.
ABSTRACT Introduction/Aims Patients with non‐length‐dependent neuropathy (NLDN) exhibit reduced sensory nerve action potential (SNAP) amplitudes in both lower and upper limbs. This study aimed to determine a threshold for the sural/radial amplitude ratio (SRAR) suggestive of NLDN.
Antoine Pegat, Antoine Gavoille, Florent Cluse, Martin Moussy, Philippe Petiot, Jean‐Philippe Camdessanché, Françoise Bouhour   +6 more
wiley   +1 more source

Ultrasound‐Guided Near‐Nerve Needle Recording in Sensory Conduction Study of the Superficial Fibular Nerve

Muscle &Nerve, Volume 73, Issue 1, Page 97-102, January 2026.
ABSTRACT Introduction/Aims The sensory nerve action potential (SNAP) of the superficial fibular nerve (SFN) is occasionally small and difficult to obtain using conventional surface recording (SR) or near‐nerve needle recording. This study aimed to demonstrate a novel method of sensory conduction study of the SFN using ultrasound‐guided near‐nerve ...
Haruki Nakano, Aishi Okazaki, Ryuichi Saura   +2 more
wiley   +1 more source

Validity and reliability of a point‐of‐care nerve conduction device in diabetes patients

Journal of Diabetes Investigation, 2019
Aims/Introduction Although nerve conduction study (NCS) using a standard electromyography system (EMGS) is considered to be the gold standard in evaluating diabetic polyneuropathy, this examination requires expensive equipment and well‐trained ...
Yuka Shibata, Tatsuhito Himeno, Taeko Kamiya, Hiroya Tani, Takayuki Nakayama, Chika Kojima, Yukako Sugiura‐Roth, Ena Naito, Masaki Kondo, Shin Tsunekawa, Yoshiro Kato, Jiro Nakamura, Hideki Kamiya   +12 more
doaj   +1 more source