Results 1 to 10 of about 76,168 (218)

IMPROVING TECHNICAL QUALITY PERFORMANCE OF REMOTE ONCO-HEMATOLOGY LABORATORY FOR BONE MARROW CYTOGENETIC ANALYSIS

Hematology, Transfusion and Cell Therapy, 2023
Introduction: This study aimed to evaluate the technical quality performance of a remote onco-hematology laboratory facility (ROLF) in Brazil, with a focus on its crucial role in the diagnosis and monitoring of onco-hematology diseases.
M Souza, A Amaro, L Fazan, R Martinez, K Tiem-Oyama, S Lanes, A Marinato, R Prot-Siqueira   +7 more
doaj   +1 more source

UNRAVELING RARE CASES IN ACUTE MYELOID LEUKEMIAS: THE SIGNIFICANCE OF SPECIALIZED REMOTE LABORATORIES IN HEMATOLOGICAL DIAGNOSIS

Hematology, Transfusion and Cell Therapy, 2023
Introduction: The diagnosis of onco-hematologic conditions in medical and hospital settings typically involves relying on centralized reference laboratories for investigative and clinical-laboratory diagnostic support.
S Lanes, LA Mattos, MAM Morais, APS Lima, C Pugliesi, M Souza, R Prot-Siqueira, A Marinato   +7 more
doaj   +1 more source

CASE REPORT: CML PROGRESSION TO AML-MR WITH CLONAL CHROMOSOMAL ABNORMALITIES

Hematology, Transfusion and Cell Therapy, 2023
Introduction: The advancement of chronic myeloid leukemia (CML) treatment through tyrosine kinase inhibitors (TKIs) has brought about a revolutionary transformation in patient outcomes, clinical responses, and survival rates.
S Lanes, WS Goulart, M Souza, L Mattos, MA Morais, AM Oba, C Pugliesi, R Prot-Siqueira, A Marinato   +8 more
doaj   +1 more source

PREVALÊNCIA DOS TRANSCRITOS DE BCR-ABL1 E TESTES CORRELATOS NO DIAGNÓSTICO DE LEUCEMIA MIELOIDE CRÔNICA EM AMOSTRAS DE ROTINA DE UM LABORATÓRIO DE GRANDE PORTE

Hematology, Transfusion and Cell Therapy, 2023
Objetivos: Identificar e relatar a prevalência dos transcritos BCR-ABL1 e testes correlatos em Leucemia Mieloide Crônica para demonstrar a sua importância na decisão diagnóstica.
KT Igari, AA Gomes, PV Macedo, LGV Nova, PY Nishimura, CAD Santos, LMR Janini, DBD Santos   +7 more
doaj   +1 more source

VALIDATION OF A RAPID AND SENSITIVE MGB PROBE-BASED REAL-TIME PCR FOR DETECTING JAK-2 V617F MUTATION

Hematology, Transfusion and Cell Therapy, 2023
Introduction: Research on point mutations in onco-hematology plays a critical role in understanding neoplasias and formulating effective treatment strategies.
C Pugliesi, RR Loiola, S Lanes, A Marinato, R Prot-Siqueira   +4 more
doaj   +1 more source

FAST AND COST-EFFECTIVE RNA EXTRACTION FOR BCR-ABL QUANTIFICATION IN ONCO-HEMATOLOGY LABORATORIES

Hematology, Transfusion and Cell Therapy, 2023
Background: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of a BCR-ABL1 rearrangement; its detection and quantification by real-time quantitative PCR (RQ-PCR) plays a central role in CML diagnosis, therapy ...
C Pugliesi, RR Loiola, S Lanes, A Marinato, R Prot-Siqueira   +4 more
doaj   +1 more source

LEUCEMIA AGUDA PROMIELOCÍTICA JUVENIL: RELATO DE CASO COM A INTEGRAÇÃO ENTRE O ESTUDO CITOMORFOLÓGICO, IMUNOFENOTÍPICO, CITOGENÉTICO E MOLECULAR

Hematology, Transfusion and Cell Therapy, 2023
Introdução: A leucemia promielocítica aguda (LPA) é um subtipo de leucemia mieloide aguda (LMA) onde a caracterização laboratorial deve ser realizada por diferentes métodos.
P Belline, FGP Cunha, N Gabur-Junior, RA Souza   +3 more
doaj   +1 more source

A Benchmark of In-House Homologous Recombination Repair Deficiency Testing Solutions for High-Grade Serous Ovarian Cancer Diagnosis

Diagnostics, 2023
Homologous recombination deficiency (HRD) has become an important prognostic and predictive biomarker for patients with high-grade serous ovarian cancer who may benefit from poly-ADP ribose polymerase inhibitors (PARPi) and platinum-based therapies.
Rodrigo Guarischi-Sousa, José Eduardo Kroll, Adriano Bonaldi, Paulo Marques Pierry, Darine Villela, Camila Alves Souza, Juliana Santos Silva, Matheus Carvalho Bürger, Felipe Azevedo Oliveira, Marcelo Gomes de Paula, Fabiana Marcelino Meliso, Luiz Gustavo de Almeida, Priscilla Morais Monfredini, Ana Gabriela de Oliveira, Fernanda Milanezi, Cristovam Scapulatempo-Neto, Guilherme Lopes Yamamoto   +16 more
doaj   +1 more source

COMPARAÇÃO DO PAINEL EUROFLOW AML/MDS E CLEARLLAB M1/M2 NA CITOMETRIA DE FLUXO HEMATOLÓGICA PARA DIAGNÓSTICO DE LMA E SMD: VANTAGENS E DESAFIOS

Hematology, Transfusion and Cell Therapy, 2023
Objetivo: Este estudo teve como objetivo comparar o painel Euroflow AML/MDS e a estratégia com tubos secos ClearLLab M1 e M2 na citometria de fluxo hematológica para o diagnóstico de leucemia mieloide aguda (LMA) e neoplasia mielodisplásica (SMD ...
GHM Oliveira, AO Sales, SDDN Medeiros, CCO Ramos, TB Guimaraes, RDA Soares, E Fernandes, MF Lima, HCG Duarte, RS Barroso   +9 more
doaj   +1 more source

Diagnóstico pouco usual de obstrução da traqueia

Revista Portuguesa de Pneumologia, 2006
Resumo: Homem, 54 anos, caucasiano e fumador, que recorreu ao serviço de urgência por apresentar tosse produtiva e expectoração hemoptóica desde há cerca de dois meses, motivo porque foi agendada broncofibroscopia. Apresentava neoformações sésseis, cerca de 2 cm abaixo das cordas vocais e ao longo da vertente póstero-lateral do terço médio
C. Damas, G. Fernandes, A. Magalhães, V.P. Hespanhol   +3 more
openaire   +2 more sources