Results 1 to 10 of about 432,175 (218)

IMPROVING TECHNICAL QUALITY PERFORMANCE OF REMOTE ONCO-HEMATOLOGY LABORATORY FOR BONE MARROW CYTOGENETIC ANALYSIS

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introduction: This study aimed to evaluate the technical quality performance of a remote onco-hematology laboratory facility (ROLF) in Brazil, with a focus on its crucial role in the diagnosis and monitoring of onco-hematology diseases.
M Souza   +7 more
doaj   +1 more source

UNRAVELING RARE CASES IN ACUTE MYELOID LEUKEMIAS: THE SIGNIFICANCE OF SPECIALIZED REMOTE LABORATORIES IN HEMATOLOGICAL DIAGNOSIS

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introduction: The diagnosis of onco-hematologic conditions in medical and hospital settings typically involves relying on centralized reference laboratories for investigative and clinical-laboratory diagnostic support.
S Lanes   +7 more
doaj   +1 more source

PREVALÊNCIA DOS TRANSCRITOS DE BCR-ABL1 E TESTES CORRELATOS NO DIAGNÓSTICO DE LEUCEMIA MIELOIDE CRÔNICA EM AMOSTRAS DE ROTINA DE UM LABORATÓRIO DE GRANDE PORTE

open access: yesHematology, Transfusion and Cell Therapy, 2023
Objetivos: Identificar e relatar a prevalência dos transcritos BCR-ABL1 e testes correlatos em Leucemia Mieloide Crônica para demonstrar a sua importância na decisão diagnóstica.
KT Igari   +7 more
doaj   +1 more source

CASE REPORT: CML PROGRESSION TO AML-MR WITH CLONAL CHROMOSOMAL ABNORMALITIES

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introduction: The advancement of chronic myeloid leukemia (CML) treatment through tyrosine kinase inhibitors (TKIs) has brought about a revolutionary transformation in patient outcomes, clinical responses, and survival rates.
S Lanes   +8 more
doaj   +1 more source

VALIDATION OF A RAPID AND SENSITIVE MGB PROBE-BASED REAL-TIME PCR FOR DETECTING JAK-2 V617F MUTATION

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introduction: Research on point mutations in onco-hematology plays a critical role in understanding neoplasias and formulating effective treatment strategies.
C Pugliesi   +4 more
doaj   +1 more source

FAST AND COST-EFFECTIVE RNA EXTRACTION FOR BCR-ABL QUANTIFICATION IN ONCO-HEMATOLOGY LABORATORIES

open access: yesHematology, Transfusion and Cell Therapy, 2023
Background: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of a BCR-ABL1 rearrangement; its detection and quantification by real-time quantitative PCR (RQ-PCR) plays a central role in CML diagnosis, therapy ...
C Pugliesi   +4 more
doaj   +1 more source

Ethnicity and the surgical management of early invasive breast cancer in over 164 000 women

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This large national study examined in detail the patterns in surgical management of early breast cancer in women of different ethnicities. Allowing for different patterns of age and stage at presentation, the surgical management of early breast cancer was similar in all women, regardless of ethnicity. All treated the same Background Limited information
T. Gathani   +4 more
wiley   +1 more source

LEUCEMIA AGUDA PROMIELOCÍTICA JUVENIL: RELATO DE CASO COM A INTEGRAÇÃO ENTRE O ESTUDO CITOMORFOLÓGICO, IMUNOFENOTÍPICO, CITOGENÉTICO E MOLECULAR

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introdução: A leucemia promielocítica aguda (LPA) é um subtipo de leucemia mieloide aguda (LMA) onde a caracterização laboratorial deve ser realizada por diferentes métodos.
P Belline   +3 more
doaj   +1 more source

Complications after medullary thyroid carcinoma surgery: multicentre study of the SQRTPA and EUROCRINE® databases

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
This study investigated postoperative complications after surgery for medullary thyroid carcinoma (MTC) in Europe. Hypoparathyroidism, recurrent laryngeal nerve palsy and bleeding requiring reoperation occurred in 170 (26·2 per cent), 62 (13·7 per cent) and 17 (2·6 per cent) patients respectively.
D.‐J. van Beek   +18 more
wiley   +1 more source

A Benchmark of In-House Homologous Recombination Repair Deficiency Testing Solutions for High-Grade Serous Ovarian Cancer Diagnosis

open access: yesDiagnostics, 2023
Homologous recombination deficiency (HRD) has become an important prognostic and predictive biomarker for patients with high-grade serous ovarian cancer who may benefit from poly-ADP ribose polymerase inhibitors (PARPi) and platinum-based therapies.
Rodrigo Guarischi-Sousa   +16 more
doaj   +1 more source

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