Results 131 to 140 of about 3,126,013 (346)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Impact from a cattle waste lagoon rupture on a downstream fish farm: a case study

open access: yesEcología Austral, 2004
A retrospective diagnosis of a massive fish mortality in an aquaculture facility was performed following a cattle waste effluent spill to a river used as source for the fish farm.
Ana De la Torre   +5 more
doaj  

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

TOWARDS ARTIFICIAL NEURAL NETWORK MODEL TO DIAGNOSE THYROID PROBLEMS [PDF]

open access: yes, 2011
Medical diagnosis can be viewed as a pattern classification problem: based a set of input features the goal is to classify a patient as having a particular disorder or as not having it.
Dr. V.Sarasvathi
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Malignant glomus tumor of jejunum with liver and peritoneum metastasis: a rare case report

open access: yesFrontiers in Oncology
Glomus tumors (GTs) are rare mesenchymal neoplasms that occur predominantly on the subungual region of the distal extremities and are rarely seen in visceral organs such as the gastrointestinal tract.
Shilan Peng   +7 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

INVESTIGATING THE EFFECT OF STRESS FACTOR ON HOMEOSTASIS AND FERTILITY OF FERTILE QUAILS

open access: yesSiberian Journal of Life Sciences and Agriculture
During the study, the influence of stress factors on the physiological state and productivity of quails was clarified and measures were taken to prevent such situations from occurring.
Arif Alirza Taghiyev   +1 more
doaj   +1 more source

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