Erratum: Preclinical study of using multiphoton microscopy to diagnose liver cancer and differentiate benign and malignant liver lesions (Erratum). [PDF]
Yan J +10 more
europepmc +1 more source
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
When Guidelines Are Not Enough: Clinician Hesitation to Diagnose Borderline Personality Disorder in Adolescents as a Barrier to Timely Evidence-Based Care. [PDF]
Shahbaz S.
europepmc +1 more source
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
A case of spontaneous acalculous gallbladder perforation difficult to diagnose on computed tomography. [PDF]
Sato M +14 more
europepmc +1 more source
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
[Statement of the Austrian Society of Pneumology expert group for interstitial lung diseases and orphan diseases on the 2025 update of the international multidisciplinary classification of interstitial pneumonias]. [PDF]
Lang D +18 more
europepmc +1 more source
Zur Ost-West-Kompetenz Berlins Versuch einer Diagnose
Angesichts des bevorstehenden Umzuges der Bundesregierung nach Berlin wird durch die Ansiedlung von Wirtschaftsverbaenden und Beratungseinrichtungen das 'Ost-West-Know-how' Berlins erweitert werden.
Internationale Akademie Schloss Baruth Stadtbuero Berlin, Berlin (Germany) +1 more
core
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source

