Results 181 to 190 of about 3,126,013 (346)

Diagnosing death [PDF]

open access: yesJournal of Paediatrics and Child Health, 2015
openaire   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

A case of spontaneous acalculous gallbladder perforation difficult to diagnose on computed tomography. [PDF]

open access: yesJ Surg Case Rep
Sato M   +14 more
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

[Statement of the Austrian Society of Pneumology expert group for interstitial lung diseases and orphan diseases on the 2025 update of the international multidisciplinary classification of interstitial pneumonias]. [PDF]

open access: yesWien Klin Wochenschr
Lang D   +18 more
europepmc   +1 more source

Zur Ost-West-Kompetenz Berlins Versuch einer Diagnose

open access: yes, 1998
Angesichts des bevorstehenden Umzuges der Bundesregierung nach Berlin wird durch die Ansiedlung von Wirtschaftsverbaenden und Beratungseinrichtungen das 'Ost-West-Know-how' Berlins erweitert werden.
Internationale Akademie Schloss Baruth Stadtbuero Berlin, Berlin (Germany)   +1 more
core  

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

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