Results 1 to 10 of about 8,019,277 (223)

Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects’ Periodontal, Glycemic, and Lipid Profiles

Journal of Diabetes Research, 2021
Background. Type 2 diabetes mellitus (T2DM) and periodontitis (P) commonly occur as comorbidities, but the commonalities in the genetic makeup of affected individuals is largely unknown. Since dyslipidemia is a frequent condition in these individuals, we
Ingra G. Nicchio, Thamiris Cirelli, Rafael Nepomuceno, Marco A. R. Hidalgo, Carlos Rossa, Joni A. Cirelli, Silvana R. P. Orrico, Silvana P. Barros, Letícia H. Theodoro, Raquel M. Scarel-Caminaga   +9 more
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Myeloid-Derived Suppressor Cells and CD68+CD163+M2-Like Macrophages as Therapeutic Response Biomarkers Are Associated with Plasma Inflammatory Cytokines: A Preliminary Study for Non-Small Cell Lung Cancer Patients in Radiotherapy

Journal of Immunology Research, 2022
Background. Recent studies show that myeloid-derived suppressor cells (MDSCs) and M2-like macrophages are involved in the treatment of tumors; however, their therapeutic response role is rarely known in non-small cell lung cancer (NSCLC) during ...
Minghe Lv, Xibing Zhuang, Shali Shao, Xuan Li, Yunfeng Cheng, Duojiao Wu, Xiangdong Wang, Tiankui Qiao   +7 more
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Assessment of Combined Karyotype Analysis and Chromosome Microarray Analysis in Prenatal Diagnosis: A Cohort Study of 3710 Pregnancies

Genetics Research, 2022
Objective. The current study aimed to compare the characteristics of chromosome abnormalities detected by conventional G-banding karyotyping, chromosome microarray analysis (CMA), or fluorescence in situ hybridization (FISH)/CNVplex analysis and further ...
Jin Wang, Danni Wang, Yan Yin, Yi Deng, Mengling Ye, Ping Wei, Zhuo Zhang, Chun Chen, Shengfang Qin, Xueyan Wang   +9 more
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Characteristics and mechanisms of mosaicism in prenatal diagnosis cases by application of SNP array

Molecular Cytogenetics, 2023
Background With the application of chromosome microarray, next-generation sequencing and other highly sensitive genetic techniques in disease diagnosis, the detection of mosaicism has become increasingly prevalent.
Lili Zhou, Huanzheng Li, Chenyang Xu, Xueqin Xu, Zhaoke Zheng, Shaohua Tang   +5 more
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Mining Potential Drug Targets and Constructing Diagnostic Models for Heart Failure Based on miRNA-mRNA Networks

Mediators of Inflammation, 2022
Heart failure (HF) is a globally prevalent cardiovascular disease, but effective drug targets and diagnostic models are still lacking. This study was designed to investigate effective drug targets and diagnostic models for HF in terms of miRNA targets ...
Xiangming Fang, Rensheng Song, Jiaxing Wei, Qin Liao, Zhenhong Zeng   +4 more
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Clinical application of chromosomal microarray analysis for fetuses with craniofacial malformations

Molecular Cytogenetics, 2020
Background The potential correlations between chromosomal abnormalities and craniofacial malformations (CFMs) remain a challenge in prenatal diagnosis.
Chenyang Xu, Yanbao Xiang, Xueqin Xu, Lili Zhou, Huanzheng Li, Xueqin Dong, Shaohua Tang   +6 more
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Sarcopenia: revised European consensus on definition and diagnosis

Age and Ageing, 2018
Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia.
A. Cruz-Jentoft, G. Bahat, J. Bauer, Y. Boirie, O. Bruyère, T. Cederholm, C. Cooper, F. Landi, Y. Rolland, A. Sayer, S. Schneider, C. Sieber, E. Topinkova, M. Vandewoude, M. Visser, M. Zamboni, I. Bautmans, J. Baeyens, M. Cesari, A. Cherubini, J. Kanis, M. Maggio, F. Martin, J. Michel, K. Pitkala, J. Reginster, R. Rizzoli, D. Sánchez-Rodríguez, J. Schols   +28 more
semanticscholar   +1 more source

Prenatal diagnosis of 7 cases with uniparental disomy by utilization of single nucleotide polymorphism array

Molecular Cytogenetics, 2021
Background The phenotypes of uniparental disomy (UPD) are variable, which may either have no clinical impact, lead to clinical signs and symptoms. Molecular analysis is essential for making a correct diagnosis.
Lili Zhou, Zhaoke Zheng, Yunzhi Xu, Xiaoxiao Lv, Chenyang Xu, Xueqin Xu   +5 more
doaj   +1 more source

Risk of Suicide After Cancer Diagnosis in England

JAMA psychiatry, 2018
Importance A diagnosis of cancer carries a substantial risk of psychological distress. There has not yet been a national population-based study in England of the risk of suicide after cancer diagnosis. Objectives To quantify suicide risk in patients with
Katherine E Henson, R. Brock, J. Charnock, B. Wickramasinghe, Olivia Will, A. Pitman   +5 more
semanticscholar   +1 more source

2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes.

European Heart Journal, 2019
Coronary artery disease (CAD) is a pathological process characterized by atherosclerotic plaque accumulation in the epicardial arteries, whether obstructive or non-obstructive.
J. Knuuti, William Wijns, A. Saraste, D. Capodanno, E. Barbato, C. Funck-Brentano, E. Prescott, Robert F. Storey, Christi Deaton, T. Cuisset, Stefan Agewall, K. Dickstein, T. Edvardsen, J. Escaned, B. J. Gersh, P. Svítil, Martine Gilard, David Hasdai, R. Hatala, Felix Mahfoud, Josep Masip, Claudio Muneretto, M. Valgimigli, Stephan Achenbach, J. J. Bax   +24 more
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