Results 171 to 180 of about 12,628,087 (402)

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

open access: yesMolecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin   +10 more
wiley   +1 more source

An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre

open access: yesHealth Technology Assessment in Action
Background: The primary aim of this study is to evaluate the role of magnetic resonance imaging (MRI) in the assessment of soft tissue tumors with histopathological correlation at a tertiary care center.
Sriramula Sripriya   +4 more
doaj  

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

open access: yesLancet Neurology, 2017
A. Thompson   +29 more
semanticscholar   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

open access: yesRevista Española de Cardiología, 2016
P. Ponikowski   +20 more
semanticscholar   +1 more source

Case for Diagnosis [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1908
openaire   +64 more sources

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf   +10 more
wiley   +1 more source

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