Results 181 to 190 of about 12,440,936 (400)

Importance of DNA Sequencing for Abnormal Hemoglobins Detected by HPLC Screening

open access: yesTurkish Journal of Hematology, 2020
Duran Canatan   +4 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Barbell Technique Associated With Sinus Lift for Horizontal and Vertical Guided Bone Regeneration—Case Report

open access: yesCase Reports in Dentistry
Conclusion: In this clinical case, for the first time in the literature, the association of the techniques allowed the regeneration of the defect, with the subsequent placement of implants in the ideal position and prosthetic rehabilitation.
Fernanda Calvo Costa   +4 more
doaj   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Identification of clusters related to programmed cell death and potential prognostic biomarkers for immunotherapy response in endometrial cancer

open access: yesScientific Reports
Endometrial cancer (EC) is one of the few malignancies with increasing incidence and mortality rates. Targeted therapy and immunotherapy have become pivotal treatment strategies for EC patients.
Shan Lu   +6 more
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy