Results 231 to 240 of about 12,810,150 (402)

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich, Tilman Schneider‐Hohendorf, Eric Baetscher, Evan L. Riddle, Marie Deffner, Emily Katsnelson, Janine Ferrant‐Orgettas, Julie Czerkowicz, John Anderson, Susan E. Goelz, Nicholas Schwab   +10 more
wiley   +1 more source

Initial Circulating CD138 Predicts End-Stage Kidney Disease in Patients with Microscopic Polyangiitis. [PDF]

Yonsei Med J
Pyo JY, Park YB, Lee SW.
europepmc   +1 more source

Comparison between transvaginal sonography, saline contrast sonovaginography and magnetic resonance imaging in the diagnosis of posterior deep infiltrating endometriosis [PDF]

, 2012
Carlo Saccardi, Erich Cosmi, A. Borghero, Alberto Tregnaghi, Salvatore Dessole, Pietro Litta   +5 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Urgent diagnosis of hereditary angioedema in the ICU and ED: the critical role of rapid complement testing - a case report. [PDF]

Int J Emerg Med
Dungan LS, Khalib K, Curley D, Keogan M.
europepmc   +1 more source

Applications of Functionalized Carbon Nanotubes for the Therapy and Diagnosis of Cancer [PDF]

, 2017
Yongsung Hwang, Sung Hoon Park, Jin Woo Lee   +2 more
openalex   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes-2026. [PDF]

Diabetes Care
American Diabetes Association Professional Practice Committee for Diabetes* .
europepmc   +1 more source

Physician's Guide to the Laboratory Diagnosis of Metabolic Diseases [PDF]

, 1997
G. M. Addison
openalex   +1 more source

Diagnosis and Management of the Metabolic Syndrome: An American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement

Current Opinion in Cardiology, 2005
S. Grundy, J. Cleeman, S. Daniels, K. Donato, R. Eckel, B. Franklin, D. Gordon, R. Krauss, P. Savage, Sidney C. Smith, J. Spertus, F. Costa   +11 more
semanticscholar   +1 more source